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1.		Dose-Finding Study Comparing Efficacy and Safety of a PARP Inhibitor Against Doxil in BRCA+ve Advanced Ovarian Cancer

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Active				18 and over				Pharmaceutical / Industry				D0810C00012 NCT00628251


2.		Phase II Study of AZD2281 in Known BRCA or Recurrent High Grade Ovarian Cancer or Known BRCA/ Triple Neg Breast Cancer

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Biomarker/Laboratory analysis, Treatment				Active				18 and over				Pharmaceutical / Industry				D0810C00020 NCT00679783


3.		Assessment of Efficacy of AZD2281 in Platinum Sensitive Serous Ovarian Cancer

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase II				Treatment				Active				18 and over				Pharmaceutical / Industry				D0810C00019 NCT00753545

First Published: 9/20/2007


4.		Phase I Study of AZD2281 and Irinotecan Hydrochloride in Patients With Locally Advanced or Metastatic Colorectal Cancer

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase I				Biomarker/Laboratory analysis, Treatment				Active				18 to 70				Other				CAN-NCIC-IND187 IND187, IND187, NCT00535353


5.		Study to Assess the Safety & Tolerability of a PARP Inhibitor in Combination With Gemcitabine in Pancreatic Cancer

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase I				Treatment				Active				18 and over				Pharmaceutical / Industry				D0810C00005 KU36-29, NCT00515866


6.		Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With Carboplatin

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase I				Treatment				Active				18 and over				Pharmaceutical / Industry				KU36-96 D0810C00004, NCT00516724


7.		Open Label, Dose Escalation Phase I Study of AZD2281

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase I				Treatment				Active				20 to 74				Pharmaceutical / Industry				D0810C00001 NCT00572364

Last Modified: 8/27/2008 First Published: 3/27/2008


8.		Phase I Study of AZD2281 and Carboplatin in Patients With BRCA1/BRCA2-Associated or Familial Metastatic or Unresectable Breast and/or Ovarian Epithelial Cancer

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase I				Biomarker/Laboratory analysis, Treatment				Active				18 and over				NCI				NCI-08-C-0092 08-C-0092, NCI-P07253, NCT00647062

Last Modified: 10/15/2008 First Published: 5/12/2008


9.		Phase I Study of PARP Inhibitor AZD2281 in Combination With Cisplatin and Gemcitabine Hydrochloride in Patients With Unresectable or Metastatic Solid Tumors

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase I				Biomarker/Laboratory analysis, Treatment				Active				18 and over				NCI				NCI-08-C-0128 08-C-0128, P07286, NCT00678132


10.		Phase I Comparative Bioavailability Study

	Phase				Type				Status				Age				Sponsor				Protocol IDs

	Phase I				Treatment				Active				18 and over				Pharmaceutical / Industry				D0810C00024 NCT00777582

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