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dimesna A synthetic derivative of dithio-ethane sulfonate with uroprotective properties. In the kidney, dimesna undergoes reduction to the free thiol compound, mesna, which reacts chemically with the urotoxic ifosfamide metabolites acrolein and 4-hydroxy-ifosfamide, resulting in their detoxification. This agent also inhibits cyclophosphamide-induced hemorrhagic cystitis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) | mesna disulfide | | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) | US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) | Tavocept | | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) | Abbreviation: | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) | DIM | | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) | Code name: | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) | BNP7787 | | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure name: | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) | 2,2'-dithio-bis-ethanesulfonate, disodium salt | | ![](https://webarchive.library.unt.edu/eot2008/20090114233144im_/http://www.cancer.gov/images/spacer.gif) |
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