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sodium salicylate The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20090114230551im_/http://www.cancer.gov/images/spacer.gif) | salicylate salicylic acid salsalate | | ![](https://webarchive.library.unt.edu/eot2008/20090114230551im_/http://www.cancer.gov/images/spacer.gif) | US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090114230551im_/http://www.cancer.gov/images/spacer.gif) | Disalcid | | ![](https://webarchive.library.unt.edu/eot2008/20090114230551im_/http://www.cancer.gov/images/spacer.gif) | Abbreviation: | ![](https://webarchive.library.unt.edu/eot2008/20090114230551im_/http://www.cancer.gov/images/spacer.gif) | Na-Sal | | ![](https://webarchive.library.unt.edu/eot2008/20090114230551im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure name: | ![](https://webarchive.library.unt.edu/eot2008/20090114230551im_/http://www.cancer.gov/images/spacer.gif) | benzoic acid, 2-hydroxy-, monosodium salt | | ![](https://webarchive.library.unt.edu/eot2008/20090114230551im_/http://www.cancer.gov/images/spacer.gif) |
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