Adrenal Function in Patients With Newly Diagnosed Lung Cancer

This study has been completed.

Sponsored by:	Princess Margaret Hospital, Hong Kong
Information provided by:	Princess Margaret Hospital, Hong Kong
ClinicalTrials.gov Identifier:	NCT00364624

Purpose

Patients with newly diagnosed lung cancer may have hypofunction of the adrenal cortex either from tumour metastasis or other mechanisms. Since lung cancer patient may have to undergo stressful investigation and treatments, undetected hypofunction of the adrenal cortex may be hazardous. Knowledge of the size of the problem may help determine whether routine check is warranted.

Condition
Lung Cancer Adrenal Insufficiency

Genetics Home Reference related topics: X-linked adrenoleukodystrophy

MedlinePlus related topics: Cancer Lung Cancer

Drug Information available for: Epinephrine Epinephrine bitartrate

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	Adrenal Cortical Function in Patients With Newly Diagnosed Lung Cancer

Further study details as provided by Princess Margaret Hospital, Hong Kong:

Biospecimen Retention: None Retained

Biospecimen Description:

Enrollment:	133
Study Start Date:	August 2006
Study Completion Date:	May 2008
Primary Completion Date:	April 2008 (Final data collection date for primary outcome measure)

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

Patients with newly diagnosed, histologically confirmed primary lung cancer

Criteria

Inclusion Criteria:

Histologically proven primary lung cancer
Newly diagnosed
No specific treatment given
No active infection in the previous week
No general anesthesia in the previous week

Exclusion Criteria:

Known adrenal disease
Receiving exogenous systemic corticosteroids
Concomitant illness known to affect adrenal function. e.g. active TB

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00364624

Locations

China, Hong Kong SAR
Department of Medicine, Princess Margaret Hospital
Kowloon, Hong Kong SAR, China

Sponsors and Collaborators

Princess Margaret Hospital, Hong Kong

Investigators

Principal Investigator:

Wai C YU, MBBS

Princess Margaret Hospital, Hong Kong

More Information

Responsible Party:	Princess Margaret Hospital, Hong Kong ( Dr. W C Yu, Consultant Physician )
Study ID Numbers:	KW/FR/06-008
Study First Received:	August 14, 2006
Last Updated:	January 15, 2009
ClinicalTrials.gov Identifier:	NCT00364624
Health Authority:	United States: Federal Government

Keywords provided by Princess Margaret Hospital, Hong Kong:

lung cancer
adrenal insufficiency

Study placed in the following topic categories:

Thoracic Neoplasms
Adrenal Insufficiency
Addison's disease
Autoimmune Diseases
Adrenal Gland Diseases
Endocrine System Diseases
Hypoadrenalism
Adrenal gland hypofunction

Respiratory Tract Diseases
Lung Neoplasms
Adrenoleukodystrophy
Lung Diseases
Addison Disease
Endocrinopathy
Epinephrine
X-linked adrenoleukodystrophy

Additional relevant MeSH terms:

Respiratory Tract Neoplasms
Neoplasms
Neoplasms by Site
Immune System Diseases

ClinicalTrials.gov processed this record on January 16, 2009