Efficacy of Retinal Nerve Fiber Layer (RNFL) / Ganglion Cell Layer Thickness Ratio by RT-View Utilizing Spectral -Domain Technology as a Diagnostic Predictor of Glaucoma.

This study is currently recruiting participants.

Verified by Yonsei University, October 2008

Sponsored by:	Yonsei University
Information provided by:	Yonsei University
ClinicalTrials.gov Identifier:	NCT00773123

Purpose

RT-View utilizes spectral domain technology to assess both RNFL and ganglion cell layer thickness. This study aims to correlate visual field defects in patients with glaucoma to both RNFL and ganglion cell layer thickness.

Condition
Primary Open Angle Glaucoma

Genetics Home Reference related topics: early-onset glaucoma

MedlinePlus related topics: Glaucoma

U.S. FDA Resources

Study Type:	Observational
Study Design:	Prospective

Further study details as provided by Yonsei University:

Primary Outcome Measures:

Ganglion cell layer thickness [ Time Frame: 1 month ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Visual field defect [ Time Frame: 1 month ] [ Designated as safety issue: No ]

Estimated Enrollment:	300
Study Start Date:	October 2008
Estimated Study Completion Date:	December 2008
Estimated Primary Completion Date:	December 2008 (Final data collection date for primary outcome measure)

Groups/Cohorts
1 Primary open angle glaucoma
2 Normal controls

Eligibility

Ages Eligible for Study:	10 Years to 90 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Probability Sample

Study Population

primary open angle glaucoma

Criteria

Exclusion Criteria:

Evidence of retinal disease
Neovascular glaucoma
Secondary glaucoma due to intraocular inflammation
Lens induced glaucoma
Tumor induced glaucoma

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00773123

Contacts

Contact: Chan Yun Kim, MD,PhD	82-2-2228-3570	kangeye@hotmail.com
Contact: Sung Yong Kang, MD	82-2-2228-3570	kangeye@yuhs.ac

Locations

Korea, Republic of
Institute of Vision Research, Department of Ophthalmology, Severance Hospital, Yonsei University School of Medicine	Recruiting
Seoul, Korea, Republic of, 120-752
Contact: Chan Yun Kim, MD,PhD 82-2-2228-3570 kangeye@hotmail.com
Contact: Sung Yong Kang, MD 82-2-2228-3570 kangeye@yuhs.ac
Principal Investigator: Chan Yun Kim, MD,PhD.

Sponsors and Collaborators

Yonsei University

More Information

Responsible Party:	Institute of Vision Research, Department of Ophthalmology, Severance Hospital, Yonsei University School of Medicine ( Kim,Chan Yun )
Study ID Numbers:	08-0342
Study First Received:	October 15, 2008
Last Updated:	October 15, 2008
ClinicalTrials.gov Identifier:	NCT00773123
Health Authority:	Korea: Food and Drug Administration

Keywords provided by Yonsei University:

RT-View
Spectral domain OCT
Ganglion cell layer
RNFL
Visual field defect

Study placed in the following topic categories:

Ganglion Cysts
Glaucoma
Eye Diseases
Glaucoma, Open-Angle

Scotoma
Hypertension
Ocular Hypertension

ClinicalTrials.gov processed this record on January 16, 2009