Morphofunctional Imaging and Developmental Dyslexia

This study has been completed.

Sponsored by:	University Hospital, Tours
Information provided by:	University Hospital, Tours
ClinicalTrials.gov Identifier:	NCT00254644

Purpose

Developmental dyslexia is a frequent learning disability. The aim of this study is to analyze cortical thickness and phonological treatment in right handed adults with developmental dyslexia. They are compared to control adults paired with age and laterality. To study phonological treatment, the researchers used functional magnetic resonance imaging (fMRI) with a rime judgement task and silent word generation.

Condition	Intervention
Developmental Dyslexia	Procedure: Morphological and functional MRI

U.S. FDA Resources

Study Type:	Observational
Study Design:	Prospective

Further study details as provided by University Hospital, Tours:

Estimated Enrollment:	30
Study Start Date:	February 2007

Eligibility

Ages Eligible for Study:	18 Years to 35 Years
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Developmental dyslexia according to Critchley.
Normal performance intelligence quotient (PIQ)
Age: 18-35 years
Right handed
No hearing deficit.

Exclusion Criteria:

No head injury
No attention deficit hyperactivity disorder (ADHD)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00254644

Locations

France
CHU
Tours, France, 37044

Sponsors and Collaborators

University Hospital, Tours

Investigators

Principal Investigator:

Frédérique Bonnet-Brilhault

CHU Tours

More Information

Responsible Party:	( University Hospital Tours )
Study ID Numbers:	PHRR04-CH/DYS
Study First Received:	November 15, 2005
Last Updated:	July 9, 2008
ClinicalTrials.gov Identifier:	NCT00254644
Health Authority:	France: Afssaps - French Health Products Safety Agency

Keywords provided by University Hospital, Tours:

phonological treatment
language
fMRI

Study placed in the following topic categories:

Signs and Symptoms
Mental Disorders
Mental Disorders Diagnosed in Childhood
Neurologic Manifestations
Language Disorders

Dyslexia
Learning Disorders
Neurobehavioral Manifestations
Communication Disorders

Additional relevant MeSH terms:

Nervous System Diseases

ClinicalTrials.gov processed this record on January 16, 2009