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Sponsors and Collaborators: |
Johns Hopkins University UCB |
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Information provided by: | Johns Hopkins University |
ClinicalTrials.gov Identifier: | NCT00370838 |
The goal of this study is to confirm that levetiracetam has a better tic-suppressing profile than that of the widely used tic-suppressing medication, clonidine. More specifically, we hypothesize that in a 15 week placebo run-in, double-blind, medication cross-over trial; levetiracetam will be more effective and have fewer side-effects than clonidine.
Condition | Intervention | Phase |
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Tic Disorders Tourette Syndrome |
Drug: levetiracetam and clonidine |
Phase IV |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double-Blind, Active Control, Crossover Assignment, Safety/Efficacy Study |
Official Title: | Comparison of Keppra and Clonidine in the Treatment of Tics in Children With Tourette Syndrome |
Estimated Enrollment: | 20 |
Study Start Date: | February 2007 |
Ages Eligible for Study: | 7 Years to 19 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Patients will be included in this study if they meet the following criteria:
Exclusion Criteria:
Exclusion criteria include the following:
Contact: Harvey S Singer, MD | 410-955-7212 | hsinger@jhmi.edu |
United States, Maryland | |
Johns Hopkins Hospital | Recruiting |
Baltimore, Maryland, United States, 21287 | |
Contact: Harvey S Singer, MD | |
Principal Investigator: Harvey S Singer, MD |
Principal Investigator: | Harvey S Singer, MD | Johns Hopkins University |
Study ID Numbers: | TSkepclon |
Study First Received: | August 30, 2006 |
Last Updated: | April 5, 2007 |
ClinicalTrials.gov Identifier: | NCT00370838 |
Health Authority: | United States: Institutional Review Board |
Tics Tourette syndrome levetiracetam clonidine |
Ganglion Cysts Clonidine Basal Ganglia Diseases Central Nervous System Diseases Tourette Syndrome Tic Disorders Neurodegenerative Diseases Brain Diseases Dyskinesias Tics |
Signs and Symptoms Heredodegenerative Disorders, Nervous System Genetic Diseases, Inborn Movement Disorders Mental Disorders Mental Disorders Diagnosed in Childhood Neurologic Manifestations Etiracetam Gilles de la Tourette's syndrome |
Nootropic Agents Sympatholytics Neurotransmitter Agents Disease Adrenergic alpha-Agonists Adrenergic Agents Molecular Mechanisms of Pharmacological Action Nervous System Diseases Physiological Effects of Drugs Cardiovascular Agents Antihypertensive Agents |
Adrenergic Agonists Pharmacologic Actions Pathologic Processes Autonomic Agents Sensory System Agents Therapeutic Uses Syndrome Peripheral Nervous System Agents Analgesics Central Nervous System Agents Anticonvulsants |