United States Department of Veterans Affairs
United States Department of Veterans Affairs
National HIV/AIDS Program
Patients' Home > Treatment > Drug Dosing Toolkit > ZiagenEnlarge Text Size:Small Font SizeMedium Font SizeLarge Font Size

Drug Dosing Toolkit

Ziagen (abacavir)

Type of Drug: Nucleoside Reverse Transcriptase Inhibitor

Nucleoside reverse transcriptase inhibitors were the first type of drug available to treat HIV. They are also known as NRTIs, nucleoside analogues, or "nukes."

When the HIV virus enters a healthy cell, it attempts to make copies of itself. It does this by using an enzyme called reverse transcriptase. NRTIs block that enzyme, so HIV cannot make new copies of itself.

Approved adult dosing

one 300 mg tablet, two times a day

  • Morning

    Ziagen 300

    Ziagen

  • Evening

    Ziagen 300

    Ziagen

two 300 mg tablets, once a day

  • Daily

    Ziagen 300Ziagen 300

    Ziagen

Notes on taking this medication

  • No food restrictions, can take with or without food

Side effects

  • Mild nausea; vomiting; diarrhea; loss of appetite
  • Rash

Caution! Ziagen can cause a serious allergic reaction that includes at least 2 of the following: fever, malaise, severe nausea, diarrhea, abdominal pain, sore throat, cough, shortness of breath, and rash. Symptoms usually begin within 6 weeks of starting medication.

If you think you are having an allergic reaction, call your doctor at once. If allergic, you will have to stop Ziagen and never take it again. Starting it again can cause serious illness or death.

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Disclaimer:

This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.