[CMND Membership Roster] [CMND Meeting Rosters]

The CMND Study Section reviews applications on cellular and molecular aspects of neurodegeneration across the lifespan; mapping novel transcripts and functional analysis of cloned gene products involved in neurodegeneration and neuroprotection; as well as molecular aspects of injury, repair and neurological disorders. Also considered are the roles of genetic factors, trophic molecules and extrinsic influences in these processes.

Specific areas covered by CMND:

• Characterization of abnormal protein processing associated with neurodegenerative disorders.
• Structure-function studies of abnormal protein folding and/or aggregation and the clearance of aggregated proteins in the context of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, transmissible spongiform encephalopathies (prion diseases), and Amyotrophic Lateral Sclerosis.
• Delineation of physiological effects of aggregated proteins (e.g., beta amyloid, tau) on neuronal function.
• Amyloidosis in the nervous system.
• Characterization of molecular mechanisms underlying triple nucleotide repeat expansion neurodegenerative disorders such as Huntington’s disease or spinocerebellar and Friedreich’s ataxias.
• Studies aimed at elucidating underlying mechanisms of neuroprotection and development of neuroprotective strategies.
• Mapping novel transcripts and functional analysis of cloned gene products involve in neurodegeneration or neuroprotection, including characterization of apolipoprotein E (ApoE) and its role in neurological and neuropathological processes.
  

Study sections with most closely related areas of science listed in rank order are:

Neural Oxidative Metabolism and Death [NOMD]
Cell Death and Injury in Neurodegeneration [CDIN]
Synapses, Cytoskeleton and Trafficking [SYN]
Clinical Neuroscience and Neurodegeneration [CNN]
Biophysics of Neural Systems [BPNS]
Cellular and Molecular Biology of Glia [CMBG]