United States Department of Veterans Affairs
United States Department of Veterans Affairs
National Hepatitis C Program
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Understanding lab tests

Hepatitis C RIBA

The hepatitis C recombinant immunoblot assay (RIBA) is the confirmation test for the hepatitis C antibody.

Explanation of test results:

If the result of the HCV RIBA is positive, this confirms that the detection of a hepatitis C antibody (anti-HCV) was a true positive, meaning that there has been infection with hepatitis C in the past.

If the HCV RIBA result is negative, it means there has not been infection with hepatitis C. If an earlier hepatitis C antibody (anti-HCV) test had been positive, then this was a false positive.

Other things to know:

  • Even if the HCV RIBA result is positive, only the test of HCV RNA (viral load) can detect whether the hepatitis C virus is still present in the body.
  • HCV RIBA is not a test that is needed for most patients. Usually, it is performed by blood banks to check for hepatitis C in people who donate blood.