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Alternate Title Study of Breast Duct Lavage, Breast Duct Endoscopy, and DNA Gene Expression Profiling in Women With Ipsilateral Breast Cancer Versus Healthy Women Who Are and Are Not at High Risk for Breast Cancer
Special Category: NIH Clinical Center trial Trial Description Diagnostic procedures, such as breast duct lavage and breast duct endoscopy, may help doctors find tumor cells early and plan better treatment for breast cancer. Studying the pattern of gene expression in breast duct cells from patients with breast cancer and from healthy participants may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. This clinical trial is studying breast duct lavage, breast duct endoscopy, and gene expression profiling to look for changes in breast duct cells in women with breast cancer compared with healthy women who are and are not at high risk for breast cancer. Eligibility criteria include the following:
Final eligibility for a clinical trial is determined by the health professionals conducting the trial. Participants will undergo breast duct lavage and breast duct endoscopy. Some participants may also undergo MRI and/or other imaging tests. Some participants may undergo a second breast duct lavage and breast duct endoscopy 3-6 months later. Breast duct cells collected during breast duct lavage will be studied in the laboratory. Important: For more details about this trial, refer to the Health Professional version of the trial summary. If you are interested in participating in a clinical trial, contact your doctor for a referral or call a trial contact person listed below. You may see the same contact person listed at more than one site, however, if you call the number listed you can ask to speak to the study coordinator or person involved with the specific trial you are interested in. If you have questions about cancer or clinical trials, call the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237). General information about clinical trials, including risks, benefits, and costs, can be found on NCI's Web site. Trial Lead Organizations NCI - Center for Cancer Research
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