![]() |
Home
Search
Study Topics
Glossary
|
![]() |
![]() |
![]() |
|
![]() |
|
![]() |
|
![]() |
|
![]() |
![]() |
![]() |
|
![]() |
Sponsors and Collaborators: |
Federal University of São Paulo Alcon Research |
---|---|
Information provided by: | Federal University of São Paulo |
ClinicalTrials.gov Identifier: | NCT00533962 |
Introduction: Ocular administration of glucocorticoids is a common and effective treatment for several ocular diseases. However it is often complicated with the elevation of intraocular pressure (IOP). Anecortave acetate (AA) is an analog of cortisol acetate and lacks the typical anti-inflammatory and immunosuppressive properties of glucocorticoids. The effect of its anterior juxtascleral depot (AJD) injection has been evaluated in cases of glaucoma caused by intravitreal triamcinolone acetonide, presenting impressive results. The purpose of this study is to evaluate the efficacy and safety of the AA injection as a possible antiglaucoma treatment alternative. Methods: A prospective clinical study will be carried out including 30 glaucoma patients (30 eyes). After inclusion each patient will receive a single AJD injection of 30 mg of AA in the selected eye. Main outcome measure include: intraocular pressure at 1st day, 7th day, 1st, 2nd and 3rd months.
Condition | Intervention |
---|---|
Glaucoma Intraocular Pressure |
Drug: Anterior Juxtascleral Depot of Anecortave Acetate |
Study Type: | Interventional |
Study Design: | Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study |
Official Title: | Anterior Juxtascleral Depot of Anecortave Acetate: Intraocular Pressure Reduction in Glaucoma Patients |
Ages Eligible for Study: | 18 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Study ID Numbers: | C-01 |
Study First Received: | September 20, 2007 |
Last Updated: | September 21, 2007 |
ClinicalTrials.gov Identifier: | NCT00533962 |
Health Authority: | Brazil: National Health Surveillance Agency |
Glaucoma Anecortave Acetate Intraocular pressure Advanced glaucoma cases with uncontrolled IOP |
Glaucoma Eye Diseases Hypertension Ocular Hypertension |