Study of the Value of Cardiac Positron Emission Tomography (PET) Scans With or Without Computed Tomography (CT) Angiography and/or Measurement of Coronary Flow Reserve

This study is enrolling participants by invitation only.

Sponsored by:	Kettering Health Network
Information provided by:	Kettering Health Network
ClinicalTrials.gov Identifier:	NCT00669968

Purpose

The purpose of this research is to determine how PET myocardial perfusion imaging involving CT angiography and measurement of coronary flow reserve affects patient care. This research will also compare the effectiveness of these scans to other similar tests and compare the cost-effectiveness of these scans to other similar tests over time.

Condition
Chest Pain Coronary Artery Disease

MedlinePlus related topics: Chest Pain Coronary Artery Disease Nuclear Scans

Drug Information available for: Adenosine

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case-Only, Prospective
Official Title:	PET Myocardial Perfusion Imaging With CT Angiography and Measurement of Coronary Flow Reserve: A Prospective Study of Effectiveness, Impact on Patient Management, Prognostic Value, and Downstream Costs

Further study details as provided by Kettering Health Network:

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	5000
Study Start Date:	February 2008
Estimated Study Completion Date:	February 2018
Estimated Primary Completion Date:	February 2013 (Final data collection date for primary outcome measure)

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Patients who undergo Rubidium PET adenosine stress test with or without CT angiography of coronary arteries and/or coronary flow reserve measurment at Kettering Medical Medical Center.

Criteria

Inclusion Criteria:

Patients referred to Kettering Medical Center for PET myocardial perfusion imaging with or without CTA and/or coronary flow reserve measurement.
Patients over 18 years of age.

Exclusion Criteria:

Patients who do not consent to participate.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00669968

Locations

United States, Ohio
Kettering Medical Center
Kettering, Ohio, United States, 45429

Sponsors and Collaborators

Kettering Health Network

Investigators

Principal Investigator:

Nathaniel Dittoe, MD

Kettering Health Network

More Information

Responsible Party:	Kettering Health Network ( Nathaniel Dittoe, M.D. )
Study ID Numbers:	07-034
Study First Received:	April 29, 2008
Last Updated:	April 30, 2008
ClinicalTrials.gov Identifier:	NCT00669968
Health Authority:	United States: Institutional Review Board

Keywords provided by Kettering Health Network:

PET myocardial perfusion imaging
Cardiac PET
Rubidium

Coronary Artery CT Angiogram
Coronary Flow Reserve
Adenosine stress test

Study placed in the following topic categories:

Arterial Occlusive Diseases
Heart Diseases
Myocardial Ischemia
Vascular Diseases
Stress
Pain
Ischemia

Arteriosclerosis
Chest Pain
Coronary Disease
Signs and Symptoms
Adenosine
Coronary Artery Disease

Additional relevant MeSH terms:

Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 16, 2009