Survey in Patients With Chronic Adrenal Insufficiency in Germany - Full Text View

Sponsored by:	University of Wuerzburg
Information provided by:	University of Wuerzburg
ClinicalTrials.gov Identifier:	NCT00444119

Purpose

The purpose of this survey is to assess patients with chronic primary or secondary adrenal failure regarding subjective health status, incidence and causes of adrenal crisis, hormone replacement regimens and concomitant endocrine or non endocrine disease.

Condition
Adrenal Insufficiency Addison's Disease

Genetics Home Reference related topics: beta-ketothiolase deficiency familial encephalopathy with neuroserpin inclusion bodies L1 syndrome leukoencephalopathy with vanishing white matter megalencephalic leukoencephalopathy with subcortical cysts X-linked adrenoleukodystrophy

MedlinePlus related topics: Addison's Disease

Drug Information available for: Epinephrine Epinephrine bitartrate

U.S. FDA Resources

Study Type:	Observational
Study Design:	Psychosocial, Cross-Sectional, Defined Population, Retrospective/Prospective Study

Further study details as provided by University of Wuerzburg:

Study Start Date:	May 2004
Estimated Study Completion Date:	April 2005

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

age > 18 years
chronic adrenal failure with disease duration > 12 months and hormone replacement therapy for cortisol deficiency

Exclusion Criteria:

adrenal insufficiency due to adrenocortical carcinoma
AI due to long-term pharmacological glucocorticoid treatment
glucocortiocid doses above 7.5 mg prednisolone equivalent for other reasons than AI

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00444119

Locations

Germany
University of Wuerzburg, Dept of Medicine - Endocrine and Diabetes unit
Wuerzburg, Germany, D-97080
Dept of Medicine, Gastroenterology, Hepatology and Endocrinology, Charité Campus Mitte, Charité, University Medicine Berlin
Berlin, Germany, D-10117

Sponsors and Collaborators

University of Wuerzburg

Investigators

Principal Investigator:

Bruno Allolio, MD

University of Wuerzburg

More Information

Publications indexed to this study:

Hahner S, Loeffler M, Fassnacht M, Weismann D, Koschker AC, Quinkler M, Decker O, Arlt W, Allolio B. Impaired subjective health status in 256 patients with adrenal insufficiency on standard therapy based on cross-sectional analysis. J Clin Endocrinol Metab. 2007 Oct;92(10):3912-22. Epub 2007 Aug 7.

Study ID Numbers:	Wü_NNRIS_45/04
Study First Received:	March 5, 2007
Last Updated:	March 5, 2007
ClinicalTrials.gov Identifier:	NCT00444119
Health Authority:	Germany: Ethics Commission

Keywords provided by University of Wuerzburg:

adrenal insufficiency
subjective health status
quality of life

adrenal crisis
hormone replacement
DHEA

Study placed in the following topic categories:

Addison's disease
Adrenal Gland Diseases
Quality of Life
Demyelinating diseases
Brain Diseases
Hypoadrenalism
Metabolism, Inborn Errors
Heredodegenerative Disorders, Nervous System
Peroxisomal Disorders
Adrenoleukodystrophy
Addison Disease
Genetic Diseases, X-Linked
Brain Diseases, Metabolic, Inborn
Epinephrine
Neurobehavioral Manifestations

X-linked adrenoleukodystrophy
Adrenal Insufficiency
Autoimmune Diseases
Metabolic Diseases
Demyelinating Diseases
Central Nervous System Diseases
Endocrine System Diseases
Adrenal gland hypofunction
Mental Retardation
Genetic Diseases, Inborn
Neurologic Manifestations
Endocrinopathy
Metabolic disorder
Brain Diseases, Metabolic

Additional relevant MeSH terms:

Immune System Diseases
Nervous System Diseases
Mental Retardation, X-Linked
Hereditary Central Nervous System Demyelinating Diseases

ClinicalTrials.gov processed this record on January 16, 2009