Exercise and Bright Light Treatment: Effects on Body Weight and Composition - Full Text View

Sponsors and Collaborators:	University Health Network, Toronto The Litebook Company Ltd
Information provided by:	University Health Network, Toronto
ClinicalTrials.gov Identifier:	NCT00384345

Purpose

Bright light therapy has been used to safely and effectively treat conditions such as Seasonal Affective Disorder and to regularize sleep in patients with circadian rhythm disorder. Based on evidence of the link between bright light, serotonin, mood and carbohydrate metabolism, it has been suggested that bright light therapy can improve weight loss but the literature on the subject is sparse. Further, the literature suggests that apart from any changes in mood and carbohydrate metabolism, bright light may reduce the unpleasant side-effects of exercise and increase compliance to an exercise program.

Condition	Intervention	Phase
Obesity Fatigue	Device: Bright Light Therapy Behavioral: Exercise	Phase II

MedlinePlus related topics: Exercise and Physical Fitness Obesity Weight Control

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety Study
Official Title:	Moderate Exercise and Bright Light Treatment in Overweight Individuals

Further study details as provided by University Health Network, Toronto:

Primary Outcome Measures:

The primary outcome measure will be the amount of weight loss.

Secondary Outcome Measures:

Secondary outcome measures will be the ratings of mood on the POMS, CES-D and SPAQ

Estimated Enrollment:	24
Study Start Date:	September 2003
Estimated Study Completion Date:	December 2003

Detailed Description:

Objective: Increased physical activity is important given the concern over the growing rates of obesity. Bright light therapy has the potential to enhancing serotonin levels, impact on carbohydrate metabolism and reducing soreness and hyperthermia associated with physical activity. The aim of this study is to conduct a controlled investigation of the effects of bright light therapy and exercise on weight loss and body composition in overweight individuals.

Research Methods and Procedures: Twenty-five overweight male and female subjects will be assigned to 6 weeks of moderate exercise with or without bright light treatment. Outcome measure included changes in body mass and body composition and ratings of mood, seasonality and sleep.

Eligibility

Ages Eligible for Study:	18 Years to 55 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Overweight subjects
Subjects in otherwise good health
Subjects willing to participate in a 6-week moderate exercise program
Bedtime between 10pm and 12am; wake-up time between 6am and 8am
Score in the median range of the Morningness/ Eveningness Questionnaire (i.e., subjects show no distinct characteristics of phase delay or phase advance)

Exclusion Criteria:

Progressive eye disease
History of cataracts, macular degeneration or have undergone laser corrective eye surgery in the past 30 days.
Currently taking any medications, e.g. antibiotics, tricyclic antidepressants, that may affect photosensitivity
History of heart disease
History of respiratory diseases, such as asthma, emphysema
Any severe or uncontrolled general medical condition
Severe psychiatric disorder (as determined by psychiatrist - CMS)
History of mania
Grossly obese individuals with morbid obesity

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00384345

Locations

Canada, Ontario
University Health Network
Toronto, Ontario, Canada, M5T 2S8

Sponsors and Collaborators

University Health Network, Toronto

The Litebook Company Ltd

Investigators

Principal Investigator:

Colin M. Shapiro, MBBCh, PhD

University Health Network, Toronto

More Information

Study ID Numbers:	03-0184-BE
Study First Received:	October 4, 2006
Last Updated:	October 4, 2006
ClinicalTrials.gov Identifier:	NCT00384345
Health Authority:	Canada: Health Canada

Keywords provided by University Health Network, Toronto:

bright light treatment
exercise
body fat index

mood
sleep
fatigue

Study placed in the following topic categories:

Body Weight
Signs and Symptoms
Obesity
Fatigue

Nutrition Disorders
Overnutrition
Overweight

ClinicalTrials.gov processed this record on January 16, 2009