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Sponsored by: |
Myeloproliferative Disorders-Research Consortium |
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Information provided by: | Myeloproliferative Disorders-Research Consortium |
ClinicalTrials.gov Identifier: | NCT00666549 |
This study that will allow for the preservation and/or storage of a small portion one or more of the following tissues:
This material will be used for the study of Myeloproliferative Disorders (MPD) by researchers. The goals of this research study are to understand the causes of MPDs, how to diagnose them more easily and how to treat them better. MPD is a disease affecting hematopoietic stem cells. Hematopoietic stem cells are cells that make blood cells. These stem cells grow in the center portion of the bones called bone marrow. Under some conditions, these cells are also found in blood. There are several diseases, which are classified as MPD. These include polycythemia vera (too many red blood cells), essential thrombocythemia (too many platelets), and idiopathic myelofibrosis (abnormal blood cells and fibers build up in the bone marrow). These syndromes carry a high risk of developing leukemia. It is important to continue to learn more about these blood cancers and to learn more about the effectiveness and potential side effects of various treatments.
Condition |
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Myelofibrosis Idiopathic Myelofibrosis Essential Thrombocythemia Polycythemia Vera |
Study Type: | Observational |
Official Title: | Research Tissue Bank |
Blood, bone marrow, bone marrow biopsy, toenail clippings, phlebotomized blood, spleen cells
Estimated Enrollment: | 400 |
Study Start Date: | September 2007 |
Estimated Study Completion Date: | December 2011 |
Estimated Primary Completion Date: | December 2011 (Final data collection date for primary outcome measure) |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Patients diagnosed with Philadelphia chromosome negative myeloproliferative disorders (MPD) polycythemia vera (PV), idiopathic myelofibrosis (IM), and essential thrombocythemia (ET) are eligible and not currently participating in any MPD-RC treatment studies.
Inclusion Criteria:
Exclusion Criteria:
Contact: Rona S Weinberg, PhD | (212) 570-3412 | rweinberg@nybloodcenter.org |
United States, California | |
Palo Alto Medical Foundation Research Institute | Recruiting |
Palo Alto, California, United States, 94301 | |
Principal Investigator: David Leibowitz, MD | |
United States, District of Columbia | |
Weill Cornell University | Recruiting |
Washington, District of Columbia, United States, 10065 | |
Principal Investigator: Tsiporah Shore, MD | |
University of Georgetown | Recruiting |
Washington, District of Columbia, United States, 20057 | |
Principal Investigator: Craig Kessler, MD | |
United States, Illinois | |
University of Illinois at Chicago | Recruiting |
Chicago, Illinois, United States, 60612 | |
Principal Investigator: Damiano Rondelli, MD | |
United States, Maryland | |
Johns Hopkins | Recruiting |
Baltimore, Maryland, United States, 21205 | |
Principal Investigator: Jerry Spivak, MD | |
United States, New York | |
Mount Sinai Medical Center | Recruiting |
New York, New York, United States, 10029 | |
Principal Investigator: Lewis Silverman, MD | |
Roswell Park | Recruiting |
Buffalo, New York, United States, 14263 | |
Principal Investigator: Minocher Battiwalla, MD | |
United States, Pennsylvania | |
University of Pennsylvania | Recruiting |
Philadelphia, Pennsylvania, United States, 19107 | |
Principal Investigator: Elizabeth Hexner, MD | |
United States, Utah | |
University of Utah | Recruiting |
Salt Lake City, Utah, United States, 84102 | |
Principal Investigator: Josef Prachal, MD | |
Italy, IL | |
Ospedali Riuniti di Bergamo | Recruiting |
Bergamo, IL, Italy | |
Principal Investigator: Alessandro Rambaldi, MD | |
University of Florence | Recruiting |
Florence, IL, Italy, 60302 | |
Principal Investigator: Alessandro Vannucchi, MD |
Study Chair: | Rona S Weinberg, PhD | Myeloproliferative Disorders-Research Consortium |
Responsible Party: | MyeloproliferativeDRC ( Rona Singer Weinberg, PhD - Study Chair ) |
Study ID Numbers: | MPD-RC 106, P01 Ca 108671-01A2 |
Study First Received: | April 23, 2008 |
Last Updated: | January 14, 2009 |
ClinicalTrials.gov Identifier: | NCT00666549 |
Health Authority: | United States: Institutional Review Board |
Myeloproliferative Disease Myelofibrosis Idiopathic Myelofibrosis Essential Thrombocythemia Polycythemia Vera |
Essential thrombocytosis Polycythemia Polycythemia Vera Myelofibrosis Hematologic Diseases Blood Platelet Disorders Blood Coagulation Disorders Myeloproliferative Disorders Polycythemia vera Hemostatic Disorders |
Myeloid Metaplasia Thrombocytopathy Myelofibrosis-osteosclerosis Lymphatic Diseases Hemorrhagic Disorders Hemorrhagic thrombocythemia Metaplasia Thrombocytosis Thrombocythemia, Hemorrhagic Bone Marrow Diseases |
Splenic Diseases |