Efficacy of Plyometrics to Increase Bone Mass in Male Cyclists With Osteopenia - Full Text View

Sponsored by:	University of Missouri-Columbia
Information provided by:	University of Missouri-Columbia
ClinicalTrials.gov Identifier:	NCT00572104

Purpose

This study will compare the ability of two types of long term (12 months) weight-bearing exercise treatments (1. high-intensity jumping and 2. weight lifting) to increase the level biochemical mediators of bone formation and reduce those of bone breakdown in male cyclists exhibiting lower than normal bone density of the spine and/or hip. Additionally, will we compare the ability of both exercise treatments to improve the accrual of bone minerals (bone mineral content) and subsequently bone strength via bone mineral density.

Condition	Intervention
Osteopenia	Other: exercise intervention

MedlinePlus related topics: Exercise and Physical Fitness Minerals

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Parallel Assignment, Efficacy Study
Official Title:	Efficacy of Plyometrics to Increase Bone Mass in Male Cyclists With Osteopenia

Further study details as provided by University of Missouri-Columbia:

Primary Outcome Measures:

Bone Mineral Density [ Time Frame: 12 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Serum markers of bone turnover [ Time Frame: 3 months ] [ Designated as safety issue: No ]
Serum hormones regulating bone turnover [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Estimated Enrollment:	40
Study Start Date:	January 2008
Estimated Study Completion Date:	July 2009

Arms	Assigned Interventions
1: Experimental 12 month resistance exercise training	Other: exercise intervention 12 month training intervention of either plyometrics or weight resistance exercise.
2: Experimental 12 month plyometric exercise training	Other: exercise intervention 12 month training intervention of either plyometrics or weight resistance exercise.

Eligibility

Ages Eligible for Study:	18 Years to 60 Years
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Male
Age 18-60 years
No symptoms of disease
Currently participating in cycling activities an average of 6 hr/wk for the previous 24 months
Osteopenia of the lumbar spine and/or hip (T score < -1.0 and > -2.5 )

Exclusion Criteria:

Medications or supplements that affect bone metabolism or prevent exercise
Previous or current medical condition affecting bone health
Osteoporosis of the lumbar spine and/or hip (T score > -1.0 or < -2.5)
Cardiovascular disease
Metallic implants
Current smoker
Current regular participation in high-intensity resistance training and/or plyometrics

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00572104

Contacts

Contact: Pamela S Hinton	573-882-4137	HintonP@missouri.edu
Contact: Matthew O Widzer	573-882-8191	mwidzer@mizzou.edu

Locations

United States, Missouri
University of Missouri-Columbia; McKee Gym
Columbia, Missouri, United States, 65211

Sponsors and Collaborators

University of Missouri-Columbia

Investigators

Principal Investigator:

Pamela S Hinton

University of Missouri-Columbia, Department of Nutritional Sciences

More Information

Responsible Party:	University of Missouri ( Pamela S. Hinton/Associate Professor )
Study ID Numbers:	1095877
Study First Received:	December 10, 2007
Last Updated:	December 10, 2007
ClinicalTrials.gov Identifier:	NCT00572104
Health Authority:	United States: Institutional Review Board

Study placed in the following topic categories:

Musculoskeletal Diseases
Bone Diseases, Metabolic
Bone Diseases

ClinicalTrials.gov processed this record on January 16, 2009