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Sponsored by: |
University of Wisconsin, Madison |
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Information provided by: | University of Wisconsin, Madison |
ClinicalTrials.gov Identifier: | NCT00205309 |
This study will examine the impact of acute illness on sequential airway IgA levels in intensive care patients who will require prolonged intubation. Infections are the most common cause of late deaths in non-head injured trauma patients and a frequent cause of morbidity and mortality in hospitalized patients, especially intubated Intensive Care Unit (ICU) patients. Nosocomial pneumonia is the most common of these infections, and its incidence in defined populations of critically injured patients is responsive to route and type of nutrition. This study will focus on the mechanisms of specific immune mucosal defenses in intestinal and extraintestinal sites and link enteral feeding (or lack of it) with maintenance (or deterioration) of respiratory mucosal defenses.
Condition |
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Intubation Critically Ill |
Study Type: | Observational |
Study Design: | Cohort, Prospective |
Official Title: | Respiratory Tract IgA Levels in Critically Ill Intubated Patients |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Intubated intensive care patients
Inclusion Criteria:
Exclusion Criteria:
Contact: Kenneth Kudsk, MD | kudsk@surgery.wisc.edu |
United States, Wisconsin | |
University of Wisconsin Hospital and Clinics | Recruiting |
Madison, Wisconsin, United States, 53792 | |
Contact: Kenneth Kudsk, MD kudsk@surgery.wisc.edu |
Principal Investigator: | Kenneth Kudsk, MD | University of Wisconsin Medical School |
Responsible Party: | University of Wisconsin ( Kenneth Kudsk, MD ) |
Study ID Numbers: | 2002-562 |
Study First Received: | September 13, 2005 |
Last Updated: | December 26, 2007 |
ClinicalTrials.gov Identifier: | NCT00205309 |
Health Authority: | United States: Institutional Review Board |
intubated patients |
Critical Illness |
Disease Attributes Pathologic Processes |