![]() |
Home
Search
Study Topics
Glossary
|
![]() |
![]() |
![]() |
|
![]() |
|
![]() |
|
![]() |
|
![]() |
![]() |
![]() |
|
![]() |
Sponsored by: |
University of Zurich |
---|---|
Information provided by: | University of Zurich |
ClinicalTrials.gov Identifier: | NCT00488384 |
Acitretin is given to hemodialysis patients who have developed in-situ or invasive squamous cell carcinoma of the skin in increasing doses up to 25 mg daily for one year.
Condition | Intervention | Phase |
---|---|---|
Carcinoma, Squamous Cell |
Drug: Chemopreventive application (Acitretin) |
Phase IV |
Study Type: | Interventional |
Study Design: | Prevention, Non-Randomized, Open Label, Historical Control, Single Group Assignment, Pharmacokinetics/Dynamics Study |
Official Title: | Acitretin Plasma Levels Under Hemodialysis |
Estimated Enrollment: | 2009 |
Study Start Date: | June 2007 |
Estimated Study Completion Date: | June 2011 |
Estimated Primary Completion Date: | December 2010 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
---|---|
a
single arm only.
|
Drug: Chemopreventive application (Acitretin)
Chemopreventive application (Acitretin)
|
Acitretin is given to hemodialysis patients who have developed in-situ or invasive squamous cell carcinoma of the skin in increasing doses up to 25 mg daily for one year. Plasma levels of acitretin will be monitored and influence of hemodialysis on acitretin plasma levels will be determined. Number of in-situ or invasive squamous cell carcinoma of the skin cases will be determined.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion criteria:
Exclusion criteria:
Contact: 01 Studienregister MasterAdmins | +41 (0)44 255 11 11 |
Switzerland | |
Clinic for Dermatology University Hospital of Zurich | Recruiting |
Zurich, Switzerland | |
Contact: Günther Hofbauer, MD hofbauer@usz.ch | |
Principal Investigator: günther Hofbauer, MD |
Study Director: | 01 Studienregister MasterAdmins | UniversitaetsSpital Zuerich |
Responsible Party: | university hospital zurich ( hofbauer ) |
Study ID Numbers: | 2007DR2065 EK674 |
Study First Received: | June 19, 2007 |
Last Updated: | June 5, 2008 |
ClinicalTrials.gov Identifier: | NCT00488384 |
Health Authority: | Switzerland: Swissmedic |
Squamous cell carcinoma of the skin under hemodialysis |
Epidermoid carcinoma Squamous cell carcinoma Carcinoma, squamous cell Neoplasms, Squamous Cell |
Carcinoma, Squamous Cell Acitretin Neoplasms, Glandular and Epithelial Carcinoma |
Keratolytic Agents Neoplasms Neoplasms by Histologic Type |
Therapeutic Uses Dermatologic Agents Pharmacologic Actions |