Photosensitivity of the Skin Under Azathioprin in Renal Transplant Recipients

This study is currently recruiting participants.

Verified by University of Zurich, June 2008

Sponsored by:	University of Zurich
Information provided by:	University of Zurich
ClinicalTrials.gov Identifier:	NCT00492895

Purpose

Photosensitivity of the skin to UVA and UVB will be determined

Condition	Intervention	Phase
Photosensitivity	Drug: Discontinuation of Azathioprin	Phase IV

MedlinePlus related topics: Kidney Transplantation

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Diagnostic, Randomized, Open Label, Dose Comparison, Crossover Assignment, Efficacy Study
Official Title:	Photosensitivity of the Skin Under Azathioprin in Renal Transplant Recipients

Further study details as provided by University of Zurich:

Primary Outcome Measures:

Photosensitivity of the skin to UVA and UVB [ Time Frame: 2 years ] [ Designated as safety issue: No ]

Estimated Enrollment:	2009
Study Start Date:	June 2007
Estimated Study Completion Date:	June 2009
Estimated Primary Completion Date:	December 2008 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
A one arm only. Crossover study	Drug: Discontinuation of Azathioprin Discontinuation of Azathioprin

Detailed Description:

Photosensitivity of the skin to UVA and UVB in renal transplant recipients with and without azathioprine will be determined. Azathioprine will be discontinued and photosensitivity determined after a wash-out period of three months

Trial with medicinal product

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion criteria:

Renal transplant recipients under azathioprin

Exclusion criteria:

Treatment with Prograf (Tacrolimus)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00492895

Contacts

Contact: Günther FL Hofbauer, MD

+41 (0)44 255 11 11

hofbauer@usz.ch

Locations

Switzerland
Clinic for Dermatology, University Hospital of Zurich	Recruiting
Zurich, Switzerland
Contact: Günther Hofbauer, MD hofbauer@usz.ch
Principal Investigator: günther hofbauer, MD

Sponsors and Collaborators

University of Zurich

Investigators

Study Director:

01 Studienregister MasterAdmins

UniversitaetsSpital Zuerich

More Information

Responsible Party:	Unversity Hospital Zürich ( Hofbauer Günther )
Study ID Numbers:	2007DR2040
Study First Received:	June 19, 2007
Last Updated:	June 5, 2008
ClinicalTrials.gov Identifier:	NCT00492895
Health Authority:	Switzerland: Swissmedic

ClinicalTrials.gov processed this record on January 16, 2009