Action of Caffeinated and Decaffeinated Espresso on Heart Rate Variability, Blood Pressure and Heart Frequency in Young Healthy Individuals - Full Text View

Sponsored by:	Charite University, Berlin, Germany
Information provided by:	Charite University, Berlin, Germany
ClinicalTrials.gov Identifier:	NCT00576030

Purpose

More than 80% of the population in the USA consume coffee each day. However there not many studies on change of heart rate variability and placebo effects after consumption of coffee.

In our study we aim to test the following hypotheses:

Habitual caffeinated espresso coffee drinkers show an increase in blood pressure, heart rate variability and parasympathetic activity (high frequency band) of the heart.
Non-habitual caffeinated espresso coffee drinkers show an increase of blood pressure. The heart rate variability and the parasympathetic activity of the heart will decrease.
Caffienated or decaffinated espresso induces comparable changes in habitual or non-habitual coffee drinkers.

Condition	Intervention
Influence of Espresso on Heart Rate Variability	Other: hab cof with water Other: hab cof with dec espresso Other: hab cof with caf espresso Other: non-hab cof with water Other: non-hab cof with dec espresso Other: non-hab cof with caf espresso

MedlinePlus related topics: Drinking Water

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case Control, Cross-Sectional

Further study details as provided by Charite University, Berlin, Germany:

Primary Outcome Measures:

Heart rate variability [ Time Frame: 70 minutes ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

blood pressure [ Time Frame: 70 min. ] [ Designated as safety issue: No ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	77
Study Start Date:	January 2007
Estimated Study Completion Date:	April 2008

Groups/Cohorts	Assigned Interventions
H habitual coffee drinkers	Other: hab cof with water habitual coffee drinker provided with water Other: hab cof with dec espresso habitual coffee drinkers given decaffeinated espresso Other: hab cof with caf espresso habitial coffee drinkers given caffeinated espresso
N non-habitual coffee drinkers	Other: non-hab cof with water non-habitial coffee drinkers given water Other: non-hab cof with dec espresso non-habitial coffee drinkers given decaffeinated espresso Other: non-hab cof with caf espresso non-habitial coffee drinkers given caffeinated espresso

Eligibility

Ages Eligible for Study:	18 Years to 50 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Probability Sample

Study Population

healthy individuals with an age between 18 and 50 years

Criteria

Inclusion Criteria:

18- 50 years old, healthy

Exclusion Criteria:

Medication, obese(BMI > 30)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00576030

Contacts

Contact: Frank Zimmermann-Viehoff, MD

+49-30-84454046

frank.zimmermann@charite.de

Locations

Germany
Department of Psychosomatic Medicine and Psychotherapy, Charité University	Recruiting
Berlin, Germany

Sponsors and Collaborators

Charite University, Berlin, Germany

More Information

Responsible Party:	Dept of Psychosomatic Medicine and Psychotherapy, Benjamin Franklin Campus, Charité,Berlin ( Prof. Dr. H.-C. Deter )
Study ID Numbers:	EA4/061/06, EA4/061/06
Study First Received:	December 14, 2007
Last Updated:	December 17, 2007
ClinicalTrials.gov Identifier:	NCT00576030
Health Authority:	Germany: Ethics Commission

Study placed in the following topic categories:

Healthy

ClinicalTrials.gov processed this record on January 16, 2009