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Sponsored by: |
State University of New York - Upstate Medical University |
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Information provided by: | State University of New York - Upstate Medical University |
ClinicalTrials.gov Identifier: | NCT00619047 |
Osteoporosis has been established as a major public health problem, primarily effecting women. The attainment of maximal peak bone mass is crucial in the prevention of osteoporosis, yet little is known about the specifics of bone accrual. Physical activity has been identified as an important modifiable factor controlling bone accrual. It is has been shown that increased activity during peri-pubertal years increase bone mineral content during adulthood. Thus, strategies designed to increase peak bone mass should target the peri-pubertal years of critical bone acquisition.
Hypothesis 1a: The amount of bone mineral accrued during the peri-pubertal years is greater in girls who engage in impact activity than in those who do not.
Hypothesis 1b: The positive effects of impact activity on bone accrual are maintained after cessation of the activity, resulting in greater bone mineral density in girls who participate in impact activity during a portion of the peri-pubertal years than in those who never participated in impact activity.
Condition |
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Accrual of Bone Mineral Content |
Study Type: | Observational |
Study Design: | Cohort, Prospective |
Official Title: | The Role of Impact Activity in Peripubertal Bone Accrual |
Enrollment: | 131 |
Study Start Date: | January 2002 |
Study Completion Date: | August 2008 |
Primary Completion Date: | August 2008 (Final data collection date for primary outcome measure) |
Groups/Cohorts |
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Observation |
Ages Eligible for Study: | 10 Years to 12 Years |
Genders Eligible for Study: | Female |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Probability Sample |
Subjects were recruited into the following three groups based on their exposure to gymnastic activity. A) control, no gymnastic activity. B)retired gymnasts, who participated at study onset, but stopped gymnastics activity during the course of the study. C) active gymnast, who continues participation in gymnastics throughout the duration of the study.
Inclusion Criteria:
Responsible Party: | SUNY Upstate Medical University ( Tamara A. Scerpella, MD ) |
Study ID Numbers: | Bone Density Study |
Study First Received: | February 6, 2008 |
Last Updated: | December 1, 2008 |
ClinicalTrials.gov Identifier: | NCT00619047 |
Health Authority: | United States: Institutional Review Board |