Comparison Between Type A Botulinum Toxin Injection and Corticosteroid Injection in the Treatment of Tennis Elbow

This study is currently recruiting participants.

Verified by E-DA Hospital, November 2006

Sponsored by:	E-DA Hospital
Information provided by:	E-DA Hospital
ClinicalTrials.gov Identifier:	NCT00395616

Purpose

Humeral lateral epicondylitis or tennis elbow is a common painful elbow disorder. The cause of tennis elbow is the chronic overload of bone-tendon junction. High prevalence of tennis elbow has a direct impact on the workplace productivity and quality of life. Steroid injection is the very few methods proved to have short-term efficacy in tennis elbow treatment, but it has potential adverse effects like tendon rupture. Temporary paralysis of muscle after botulinum toxin injection may reduce the physical demands and facilitate the normal repair mechanism during recovery. Preliminary studies suggested that botulinum toxin injection is effective in treating tennis elbow. The objective of this study is to compare the effects of botulinum toxin injection with corticosteroid injection in tennis elbow treatment.

Condition	Intervention
Type A Botulinum Toxin Tennis Elbow	Drug: Botox (drug)

MedlinePlus related topics: Elbow Injuries and Disorders

Drug Information available for: Corticosteroids Clostridium botulinum toxin

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Active Control, Parallel Assignment

Further study details as provided by E-DA Hospital:

Primary Outcome Measures:

WHOQOL-BREF
visual analogue scale for pain
grip strength

Estimated Enrollment:	40
Study Start Date:	November 2006

Eligibility

Ages Eligible for Study:	20 Years to 80 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Pain at the lateral epicondyle of the elbow
Tenderness at the lateral epicondyle of the elbow
Pain on resisted extension of the wrist

Exclusion Criteria:

Local injection of steroid within 3 months
Previous elbow trauma or operations
Pregnancy
Systemic neuromuscular disorders such as myasthenia gravis

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00395616

Contacts

Contact: Yu-Ching Lin, MD

886-7-6150011 ext 2367

yuchinglin2003@yahoo.com.tw

Locations

Taiwan
E-Dah Hospital	Recruiting
Kaohsiung,, Taiwan, 833
Contact: Yu-Ching Lin, MD 886-7-6150011 ext 2367 yuchinglin2003@yahoo.com.tw

Sponsors and Collaborators

E-DA Hospital

Investigators

Study Chair:

Yu-Ching Lin, MD

E-Dah Hospital, Kaohsiung, Taiwan

More Information

Study ID Numbers:	e120537192
Study First Received:	November 2, 2006
Last Updated:	November 2, 2006
ClinicalTrials.gov Identifier:	NCT00395616
Health Authority:	Taiwan: Department of Health

Study placed in the following topic categories:

Botulinum Toxins
Musculoskeletal Diseases
Tennis Elbow
Wounds and Injuries

Disorders of Environmental Origin
Botulinum Toxin Type A
Arm Injuries

ClinicalTrials.gov processed this record on January 16, 2009