Optical Coherence Tomography Measurements in Eyes With Band Atrophy

This study has been completed.

Sponsors and Collaborators:	University of Sao Paulo Fundação de Amparo à Pesquisa do Estado de São Paulo
Information provided by:	University of Sao Paulo
ClinicalTrials.gov Identifier:	NCT00395122

Purpose

The study is designed to evaluate the ability of optical coherence tomography and VCC scanning laser polarimetry to measure and identify the pattern of band atrophy of the optic nerve in patients with long standing chiasmal lesions. The hypothesis is that these new technologies are able to identify such pattern. The idea is that by using eyes with band atrophy one is able to investigate the ability of the new technologies in measuring the retinal nerve fiber layer particularly in the nasal and temporal portions of the optic nerve.

Condition	Intervention
Vision Disorders	Device: Retinal nerve fiber layer and macular thickness measurements

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Diagnostic, Non-Randomized, Open Label, Historical Control, Parallel Assignment, Efficacy Study
Official Title:	Evaluation of the Diagnostic Ability of Optical Coherence Tomography With a Normative Database to Detect Band Atrophy of the Optic Nerve

Further study details as provided by University of Sao Paulo:

Primary Outcome Measures:

Retina nerve fiber layer measurements
Macular thickness measurements

Estimated Enrollment:	30
Study Start Date:	April 2005
Estimated Study Completion Date:	October 2006

Eligibility

Ages Eligible for Study:	18 Years to 70 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:Patients with long standing chiasmal lesions and temporal visual field defect with the following criteria:

Visual acuity better than 20/30
Refractive error less 5 spherical diopter and 3 cylinder diopter
Temporal field defect

Exclusion Criteria:

Presence of glaucoma and optic nerve anomalies
Anormal nasal field

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00395122

Sponsors and Collaborators

University of Sao Paulo

Fundação de Amparo à Pesquisa do Estado de São Paulo

Investigators

Principal Investigator:

Mário LR Monteiro, MD, PhD

University of São Paulo Medical School

More Information

Study ID Numbers:	OCT in band atrophy, FAPESP grant No 05/55326-1
Study First Received:	November 1, 2006
Last Updated:	November 1, 2006
ClinicalTrials.gov Identifier:	NCT00395122
Health Authority:	Brazil: Ministry of Health

Keywords provided by University of Sao Paulo:

Band Atrophy
Optical Coherence Tomography
Scanning Laser Polarimetry
Chiasmal Lesions

Study placed in the following topic categories:

Pathological Conditions, Anatomical
Signs and Symptoms
Sensation Disorders
Vision Disorders

Eye Diseases
Neurologic Manifestations
Atrophy

Additional relevant MeSH terms:

Nervous System Diseases

ClinicalTrials.gov processed this record on January 16, 2009