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Sponsors and Collaborators: |
Imperial College London Masterfoods |
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Information provided by: | Imperial College London |
ClinicalTrials.gov Identifier: | NCT00125866 |
The purpose of this study is to compare the effects on blood pressure of a daily intake of a flavonoid-rich cocoa drink with that of the same drink from which the flavonoids have been largely extracted.
Condition | Intervention |
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Hypertension |
Behavioral: Flavonoid rich or flavonoid depleted chocolate drink |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study |
Official Title: | The Effect of Cocoa Polyphenols on Various Cardiovascular Measurements Including Blood Pressure |
Estimated Enrollment: | 50 |
Study Start Date: | September 2005 |
Study Completion Date: | January 2006 |
Flavonoids are natural substances found in fruits and vegetables, tea and red wine. The investigators know that people who eat a diet rich in these foods are less likely to have heart disease. This, in part, may be due to the blood pressure lowering effect of flavonoids. Cocoa beans are a rich natural source of flavonoids. Unfortunately when cocoa is made into chocolate most of the flavonoids are destroyed. The aim of this study is to find out the effect of cocoa flavonoids on blood pressure after 12 weeks of daily consumption of a specially prepared chocolate drink that is rich in flavonoids.
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
United Kingdom, London | |
Imperial College London | |
Paddington, London, United Kingdom, W2 1PG |
Principal Investigator: | Neil R Poulter | Imperial College London |
Study ID Numbers: | NPSW01 |
Study First Received: | July 29, 2005 |
Last Updated: | April 16, 2007 |
ClinicalTrials.gov Identifier: | NCT00125866 |
Health Authority: | United Kingdom: Research Ethics Committee |
randomised double blind trial blood pressure cocoa flavonoids |
Vascular Diseases Hypertension |
Cardiovascular Diseases |