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Sponsors and Collaborators: |
University Hospital, Basel, Switzerland Bayer |
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Information provided by: | University Hospital, Basel, Switzerland |
ClinicalTrials.gov Identifier: | NCT00139984 |
The purpose of this study is to determine whether in patients with arterial hypertension, treatment guidance using 24-hour blood pressure measurement results in better blood pressure control compared to treatment guidance using office blood pressure measurement.
Condition | Intervention | Phase |
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Hypertension |
Device: 24 hour blood pressure measurement |
Phase IV |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Efficacy Study |
Official Title: | Impact of Ambulatory Blood Pressure Monitoring for Antihypertensive Treatment Guidance in Medical Outpatients: The Hyper-ABC Study |
Estimated Enrollment: | 170 |
Study Start Date: | October 2003 |
Study Completion Date: | May 2007 |
Blood pressure control in arterial hypertension remains poor, despite the availability of effective drug treatment. Therefore, strategies to increase blood pressure control are urgently needed. 24 hour blood pressure is a better predictor of cardiovascular morbidity and mortality than office blood pressure. Furthermore, the lower variability of measurements over time of 24 hour blood pressure could allow better adjustment of antihypertensive therapy. However, there are only scarce data about antihypertensive treatment adjustment using 24 hour blood pressure instead of office blood pressure.
Aim: To test the hypothesis that a 24 hour blood pressure guided therapy is is more effective in reaching blood pressure control when compared to conventional office blood pressure guided therapy.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Switzerland | |
Medical Outpatient Clinic, University Hospital Basel | |
Basel, Switzerland, 4031 | |
Private Practice | |
Basel, Switzerland, 4057 |
Principal Investigator: | David Conen, MD | Cardiology, University Hospital Basel |
Principal Investigator: | Benedict Martina, MD | Medical Outpatient Clinic, University Hospital Basel |
Study ID Numbers: | EKBB183/03 |
Study First Received: | August 29, 2005 |
Last Updated: | August 29, 2007 |
ClinicalTrials.gov Identifier: | NCT00139984 |
Health Authority: | Switzerland: Swissmedic |
Hypertension Ambulatory blood pressure monitoring Blood pressure Risk assessment |
Vascular Diseases Hyperkinesis Hypertension |
Cardiovascular Diseases |