All populations (neonatal, pediatrics, and adults).

Inclusion Criteria:

• Signed informed consent from subject and/or guardian
• Ability to maintain proper placement of cuff and/or probe and/or sensor
• Presence of atrial fibrillation or other irregular heart rhythm (when applicable)
• Ability to single or dual monitor NIBP, ECG, and/or SpO2, whether or not already being monitored for any or all of these parameters (SuperSTAT development study only)

Exclusion Criteria:

• Any subject deemed too unstable, by clinician's discretion, or for another reason deemed unacceptable for study by the clinician
• Known dysrhythmias (when applicable)
• Known disease state or medical condition that A) compromises circulation to the extremity, B) compromises musculo-skeletal integrity, or C) otherwise contraindicates use of a NIBP cuff and/or SpO2 sensor on an extremity or ECG patches on skin
• Vigorous exercise prior to participating in the study
• Excessive movement or excitability causing false values or no determinations
• Known allergy to latex when latex products will be in contact with subject
• Subjects who have eaten, drank, smoked or chewed gum in the preceding half hour (temperature parameter only)
• Nasal/septal defects, cold and/or allergies that would not allow the subject to breathe through their nose (temperature parameter only)
• Subjects with whom flammable anesthetics will be used.
• Adult/pediatric subjects,(greater than 1 year of age) who, at the clinician's discretion, could not tolerate approximately 12, but no more than 25 blood pressures on each extremity
• Pediatric/neonatal subjects,(less than 1 year of age) who, at the clinician's discretion, could not tolerate approximately 10, but no more than 12 blood pressures on each extremity
• Presence of pacemaker which makes the atrial fibrillation rhythm indistinguishable
• Subject's limb circumference is outside of the manufacturer's recommended cuff range
• Subject has Korotkoff sounds that persist to nearly zero (when applicable)