Inclusion Criteria:

• Male or female, ≥40 years of age, Current or previous cigarette smoker with a history of cigarette smoking of ≥10 pack-years, Self reported symptoms of chronic bronchitis where chronic bronchitis is defined as the presence of productive cough for at least 3 months in each of the successive 2 years, Completion of written informed consent prior to study participation, subject must be able to read, comprehend, and record information in English.

Exclusion Criteria:

• Regular use (i.e., prescribed for use on a daily basis) of the following respiratory medications for the six months prior to the study visit: ipratropium, ipratropium/albuterol combinations, tiotropium, salmeterol, formoterol, inhaled corticosteroids, inhaled corticosteroid/long-acting beta-agonist combinations, theophyllines, oral beta-agonists. Previous lung surgery, including, lung transplant, lung resection, lung volume reduction surgery, etc. Current diagnosis of a significant lung condition other than chronic bronchitis, including, asthma, lung cancer, cystic fibrosis, pulmonary fibrosis, bronchiectasis, active tuberculosis, sarcoidosis, or alpha-1-antitrypsin deficiency. Any medical or physical condition that would interfere with the adequate performance of spirometry. Evaluation and/or treatment by a pulmonary specialist (e.g., pulmonologist or allergist) within 3 years of the study visit. A spirometrically confirmed diagnosis of COPD. Have, in the opinion of the investigator, evidence of current alcohol, illegal drug or solvent abuse. Limited ability to provide a valid informed consent due to serious uncontrolled psychiatric disease, intellectual or cognitive deficiency, poor motivation or other relevant condition which in the opinion of the site principal investigator will interfere with the subject's participation in the study. Pregnant females. Is a participating investigator, sub-investigator, study coordinator, employee of the participating investigator or family members of the aforementioned site staffs