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Sponsors and Collaborators: |
Institut National de la Santé Et de la Recherche Médicale, France Ministry of Health, France |
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Information provided by: | Institut National de la Santé Et de la Recherche Médicale, France |
ClinicalTrials.gov Identifier: | NCT00142363 |
The DNA and Cell Bank of Instituts Federatifs de Recherche (IFR) of Neurosciences has been running for the last 15 years at the Institut National de la Santé Et de la Recherche Médicale (INSERM) Unit 679 (former unit 289). Since its creation, this structure has been the support of research projects in genetics for neurological and psychiatric disorders. The cohorts established have led to discoveries in monogenic disorders, such as cerebellar ataxias, spastic paraplegias, frontotemporal dementias, epilepsies, Parkinson’s and Alzheimer’s disease, Charcot-Marie-Tooth disease and related entities. The research projects based on the study of the genetic bases in Parkinson’s disease and epilepsies are especially developed for this grant.
Concerning Parkinson’s disease, the project is based on the extension of the existing cohort throughout the French Parkinson’s Disease Study Group network. Concerning epilepsies, this project is the occasion to build this network with the constitution of a new cohort.
The specific aims of the scientific projects are the following for Parkinson’s disease:
For epilepsies, the aims are:
Study Type: | Observational |
Study Design: | Natural History, Longitudinal, Case Control, Prospective Study |
Official Title: | The DNA and Cell Bank of IFR of Neurosciences: Clinical and Genetic Study of Parkinson's Disease and Epilepsies |
Ages Eligible for Study: | 1 Year to 90 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
France | |
Centre Hospitalier du Pays d'Aix | |
Aix-en-Provence, France, 13616 | |
CHU de Grenoble | |
Grenoble, France, 38000 | |
Hôpital Civil | |
Strasbourg, France, 67000 | |
Hôpital Gabriel Montpied | |
Clermont-Ferrand, France, 63000 | |
Hôpital Haut-Lévêque | |
Pessac, France, 33604 | |
Hôpital Neurologique Pierre Wertheimer | |
Lyon, France, 69003 | |
Hôpital Pitié-Salpêtrière | |
Paris, France, 75013 | |
Hôpital Robert Debré | |
Paris, France, 75019 | |
Hôpital Purpan | |
Toulouse, France, 31000 | |
Hôpital René et Guillaume Laennec | |
Nantes, France, 44000 | |
Hôpital Roger Salengro | |
Lille, France, 59000 | |
Hôpital Saint-Antoine | |
Paris, France, 75012 | |
Pitié-Salpêtrière Hospital - Centre of Clinical Investigations | |
Paris, France, 75013 | |
Hôpital Pasteur | |
Nice, France, 06000 | |
Hôpital Pontchaillou | |
Rennes, France, 35000 |
Principal Investigator: | Alexis Brice, MD | Assistance Publique - Hôpitaux de Paris, University Paris 6 |
Study ID Numbers: | 4CH03G |
Study First Received: | September 1, 2005 |
Last Updated: | February 28, 2006 |
ClinicalTrials.gov Identifier: | NCT00142363 |
Health Authority: | France: Ministry of Health |
Parkinson's disease Parkin Epilepsy Phenotype-genotype correlations Ionic channels |
Ganglion Cysts Movement Disorders Parkinson Disease Epilepsy Basal Ganglia Diseases |
Central Nervous System Diseases Parkinsonian Disorders Neurodegenerative Diseases Brain Diseases |
Nervous System Diseases |