Airway Inflammation in Swimmers

This study is enrolling participants by invitation only.

Sponsors and Collaborators:	Bispebjerg Hospital Imperial College London The Health Insurance Foundation Toyota-Fonden Team Danmark Anti Doping Danmark Ragnhild Ibsens Legat for Medicinsk Forskning Kong Christian IX og Dronning Louises Jubilæumslegat Kong Christian den Tiendes Fond
Information provided by:	Bispebjerg Hospital
ClinicalTrials.gov Identifier:	NCT00207038

Purpose

Studies have shown that the prevalence of respiratory symptoms, airway hyperresponsiveness (AHR) and asthma is high and increasing in elite athletes. The inflammation seen in the airways of elite athletes might differ from the inflammation seen in the airways of "ordinary" asthmatics and it might represent a different kind of asthma.

The primary purposes are

To investigate the type of airway inflammation in young swimmers.
To investigate the acute changes in airway inflammation after a short training session

Condition
Asthma

MedlinePlus related topics: Asthma

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Cross-Sectional
Official Title:	Airway Inflammation in Swimmers: Development and Risk Factors

Further study details as provided by Bispebjerg Hospital:

Biospecimen Retention: Samples Without DNA

Biospecimen Description:

Blood samples EBC Sputum

Estimated Enrollment:	90
Study Start Date:	September 2005
Estimated Study Completion Date:	September 2009

Eligibility

Ages Eligible for Study:	10 Years to 16 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

Elite swimmers

Criteria

Inclusion Criteria:

Swimmer

Exclusion Criteria:

Current smoker or more than 3 pack-years

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00207038

Locations

Denmark
Respiratory and Allergy Research Unit, Department of Internal Medicine, Bispebjerg Hospital, University Hospital of Copenhagen
Copenhagen, Denmark, 2400

Sponsors and Collaborators

Bispebjerg Hospital

Imperial College London

The Health Insurance Foundation

Toyota-Fonden

Team Danmark

Anti Doping Danmark

Ragnhild Ibsens Legat for Medicinsk Forskning

Kong Christian IX og Dronning Louises Jubilæumslegat

Kong Christian den Tiendes Fond

Investigators

Study Chair:

Lars Pedersen, MD

Respiratory and Allergy Reseach Unit, Department of Internal Medicine, Bispebjerg Bakke 23, Bispebjerg Hospital, University Hospital of Copenhagen, DK-2400 Copenhagen NV, Denmark

More Information

Responsible Party:	Bispebjerg Hospital ( Lars Pedersen )
Study ID Numbers:	(KF) 01 261528
Study First Received:	September 14, 2005
Last Updated:	September 30, 2008
ClinicalTrials.gov Identifier:	NCT00207038
Health Authority:	Denmark: Ethics Committee

Keywords provided by Bispebjerg Hospital:

Asthma
Airway inflammation
Sport

Study placed in the following topic categories:

Hypersensitivity
Lung Diseases, Obstructive
Respiratory Tract Diseases
Lung Diseases

Hypersensitivity, Immediate
Asthma
Respiratory Hypersensitivity
Inflammation

Additional relevant MeSH terms:

Pathologic Processes
Immune System Diseases
Bronchial Diseases

ClinicalTrials.gov processed this record on January 16, 2009