PET Study in Panic Disorder According to Paroxetine Treatment

This study is currently recruiting participants.

Verified by Samsung Medical Center, August 2007

Sponsored by:	Samsung Medical Center
Information provided by:	Samsung Medical Center
ClinicalTrials.gov Identifier:	NCT00515749

Purpose

We plan to examine the activity of brain fear network in panic disorder before and after pharmacotherapy with paroxetine using FDG-PET.

Condition
Panic Disorder

MedlinePlus related topics: Panic Disorder

Drug Information available for: Paroxetine Paroxetine hydrochloride Paroxetine Mesylate Dextrose

U.S. FDA Resources

Study Type:	Observational
Study Design:	Longitudinal, Case Control, Prospective Study
Official Title:	Changes of Cerebral Glucose Metabolism Associated With the Fear Network Activity Before and After 12 Weeks of Paroxetine Treatment in Panic Disorder

Further study details as provided by Samsung Medical Center:

Estimated Enrollment:	40
Study Start Date:	January 2007
Estimated Study Completion Date:	December 2008

Groups/Cohorts
2: Case Paroxetine treatment group vs. Normal Control group

Eligibility

Ages Eligible for Study:	20 Years to 60 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Right-handed unmedicated panic disorder

Exclusion Criteria:

Comorbid other major medical or psychiatric illnesses

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00515749

Contacts

Contact: Tae Geun Kim, BA

82-2-3410-2975

tggo.kim@samsung.com

Locations

Korea, Republic of
Samsung Medical Ceter	Recruiting
Seoul, Korea, Republic of, 135-710
Contact: Tae Geun Kim, BA 82-2-3410-2975 tggo.kim@samsung.com
Principal Investigator: Bum-Hee Yu, M.D. & Ph.D.

Sponsors and Collaborators

Samsung Medical Center

Investigators

Principal Investigator:

Bum-Hee Yu, M.D. & Ph.D.

Samsung Medical Center, Sungkyunkwan University School of Medicine

More Information

Study ID Numbers:	CRS107-18-1
Study First Received:	August 13, 2007
Last Updated:	August 13, 2007
ClinicalTrials.gov Identifier:	NCT00515749
Health Authority:	South Korea: Samsung Medical Center

Keywords provided by Samsung Medical Center:

panic disorder
FDG-PET
paroxetine

Study placed in the following topic categories:

Panic Disorder
Anxiety Disorders
Mental Disorders
Paroxetine
Serotonin

Additional relevant MeSH terms:

Neurotransmitter Uptake Inhibitors
Neurotransmitter Agents
Disease
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
Psychotropic Drugs
Serotonin Uptake Inhibitors

Pharmacologic Actions
Pathologic Processes
Serotonin Agents
Therapeutic Uses
Antidepressive Agents, Second-Generation
Central Nervous System Agents
Antidepressive Agents

ClinicalTrials.gov processed this record on January 16, 2009