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Cortical Reorganisation in Patients With Primary Headache Disorders
This study is ongoing, but not recruiting participants.
Sponsored by: Danish Headache Center
Information provided by: Danish Headache Center
ClinicalTrials.gov Identifier: NCT00263991
  Purpose

Primary headache disorders are now accepted as physiological diseases, and advanced imaging-techniques have demonstrated a migraine generator in the brain stem and increased stimulus sensitivity in these patients. The underlying neuronal dysfunctions remain to to clarified and the existing neurophysiological methods have not yet been useful. More sensitive and reliable methods are therefore highly needed. The aims of the study are therefore to develop a sensitive and reliable method to demonstrate a cortical reorganisation and expansion of pain sensitive cortical areas in patients with migraine or tension-type headache.


Condition Intervention
Migraine Without Aura
Chronic Tension-Type Headache
Device: EEC-techniques

Genetics Home Reference related topics: familial hemiplegic migraine
MedlinePlus related topics: Headache Migraine
U.S. FDA Resources
Study Type: Observational
Study Design: Screening, Cross-Sectional, Case Control, Prospective Study
Official Title: Cortical Reorganisation in Patients With Primary Headache Disorders
  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Clinical diagnosis og migraine without aura or chronic tension-type headache

Exclusion Criteria:

  • serious somatic or psychiatric diseases including depression
  • overuse of analgesics
  • regular intake of opiates or benzodiazepines
  • intake of prophylactic headache medication
  • pregnancy
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00263991

Locations
Denmark
Danish Headache Center; Department of Neurology, Glostrup Hospital, University of Copenhagen
Glostrup, Copenhagen, Denmark, 2600
Sponsors and Collaborators
Danish Headache Center
Investigators
Principal Investigator: Lars Bendtsen, MD, Ph.d Danish Headache Center, Department of Neurology, Glostrup Hospital, University of Copenhagen, Denmark
  More Information

Study ID Numbers: KA 05085
Study First Received: December 9, 2005
Last Updated: December 9, 2005
ClinicalTrials.gov Identifier: NCT00263991  
Health Authority: Denmark: National Board of Health

Study placed in the following topic categories:
Signs and Symptoms
Migraine Disorders
Tension-Type Headache
Headache
Central Nervous System Diseases
Neurologic Manifestations
Pain
Headache Disorders, Primary
Brain Diseases
Headache Disorders
Migraine without Aura

Additional relevant MeSH terms:
Nervous System Diseases

ClinicalTrials.gov processed this record on January 16, 2009