Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder - Full Text View

Sponsored by:	Hospices Civils de Lyon
Information provided by:	Hospices Civils de Lyon
ClinicalTrials.gov Identifier:	NCT00131781

Purpose

This is a randomised trial comparing cognitive therapy and supportive therapy administered along one year in borderline personality disorder. The follow-up is one year after treatments end.

The therapists were the same in the two groups. Patients received one session a week during six months and one session every two weeks during the next six months

Condition	Intervention
Borderline Personality Disorder	Behavioral: Cognitive Therapy Behavioral: Supportive Therapy

MedlinePlus related topics: Personality Disorders Suicide

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Randomized, Single Blind, Active Control, Parallel Assignment
Official Title:	Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder

Further study details as provided by Hospices Civils de Lyon:

Primary Outcome Measures:

Clinical Global Impression (CGI): Improvement (1-7): score 3 ( a little better) associated with a hopelessness scale score < 8 (this means that the suicide risk is low)

Secondary Outcome Measures:

CGI severity and improvement
Hamilton depression
Beck Depression Inventory
Hopelessness
Young: Schema Questionnaire II
Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Personality Disorders Personality Questionnaire (SCID II PQ)
Minnesota Multiphasic Personality Inventory (MMPI) (minimult)
Eysenck: impulsivity scale
Checklist: impulsive risky behaviors
Quality of life
Handicap (Sheehan)
Time: Pre test, six months, post test and one year post treatment follow-up
Therapeutic relationship evaluation scale (patients and therapists)

Estimated Enrollment:	70
Study Start Date:	March 2001

Detailed Description:

Cognitive Therapy
Structured session
Conceptualization of the case with the patient
Cognitive methods
Guided discovery of the schemas
Work on life-scenarios
From scenarios to schemas
Empathic confrontation to the schemas
Building new schemas (Core belief work-sheet)
Affective methods: role playing
Interpersonal methods: counter transference issues
Behavioral experiment
Problem solving
Consolidation methods
Patients and therapists had manuals
Supportive Therapy
Therapist: active listening (face to face)
Empathy
Unconditional positive regard
Reformulation and clarification
Reflection of the patient’s feelings
Reassurance
Therapist emphasizes the importance to ventilate problems
Therapist answers some factual questions
Therapist politely ignore or refuse requests for advice and directive attitudes
Therapist demonstrates warmth and genuineness
Patients and therapists had manuals

Eligibility

Ages Eligible for Study:	18 Years to 65 Years
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

DSM-4 DIBR >=8 (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Diagnostic inventory for borderline-revised)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00131781

Locations

France
Hopital Pierre Wertheimer
BRON, France, 69677

Sponsors and Collaborators

Hospices Civils de Lyon

Investigators

Principal Investigator:

Jean COTTRAUX, MD

Hospices Civils de Lyon

More Information

Study ID Numbers:	2000.230
Study First Received:	August 18, 2005
Last Updated:	April 26, 2007
ClinicalTrials.gov Identifier:	NCT00131781
Health Authority:	France: Ministry of Health

Keywords provided by Hospices Civils de Lyon:

Borderline personality disorder
Controlled trials
Cognitive Therapy

Supportive Therapy
suicide
impulsivity

Study placed in the following topic categories:

Mental Disorders
Suicide
Borderline Personality Disorder
Personality Disorders

Additional relevant MeSH terms:

Pathologic Processes
Disease

ClinicalTrials.gov processed this record on January 16, 2009