Hormonal Levels in Men With Major Depressive Disorder - Full Text View

Sponsored by:	Sheba Medical Center
Information provided by:	Sheba Medical Center
ClinicalTrials.gov Identifier:	NCT00429689

Purpose

Subjects will be 1000 men meeting the following inclusion criteria: 1) male, age 18-65 years; 2) meeting DSM-IV criteria for major depressive disorder within the past one year, with a HAM-D score >12.

Subjects will be excluded if they exhibit 1) a substance abuse or dependence disorder within the past year; 2) current psychotic symptoms; or 3) a history of bipolar disorder.

Procedure

After informed consent, eligible patients will have blood drawn for serum hormone levels; cortisol, DHEA-S and tostestesterone or they will provide a salivary sample for measurement of hormone levels.

We will also test hormone level form 1000 healthy males (from blood or saliva) at the same age for comparison.

Condition	Intervention
Depression	Procedure: Saliva sumple

MedlinePlus related topics: Depression

Drug Information available for: Hydrocortisone Cortisol 21-phosphate Cortisol succinate Hydrocortamate Hydrocortisone 21-sodium succinate Hydrocortisone acetate Hydrocortisone cypionate Hydrocortisone hemisuccinate Proctofoam-HC

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening, Longitudinal, Defined Population, Retrospective Study
Official Title:	Hormonal Levels in Men With Major Depressive Disorder

Further study details as provided by Sheba Medical Center:

Estimated Enrollment:

2000

Eligibility

Ages Eligible for Study:	18 Years to 65 Years
Genders Eligible for Study:	Male

Criteria

Inclusion Criteria:

Male
Major Depression Disorder
18-65

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00429689

Contacts

Contact: Revital Amiaz, MD

+972-52-6666571

revital.amiaz@sheba.health.gov.il

Sponsors and Collaborators

Sheba Medical Center

Investigators

Study Director:	Stuart Seidman,, MD	West End Medical Associates
Principal Investigator:	Revital Amiaz, MD	Sheba Medical Center

More Information

Study ID Numbers:	SHEBA-06-4480-RA-CTIL
Study First Received:	January 31, 2007
Last Updated:	January 31, 2007
ClinicalTrials.gov Identifier:	NCT00429689
Health Authority:	Israel: The Israel National Institute for Health Policy Research and Health Services Research

Keywords provided by Sheba Medical Center:

Male, MDD, Tostesterone, DHEA-S,Cortisol
Male
18-65
Major Depression

Study placed in the following topic categories:

Hydrocortisone
Depression
Cortisol succinate
Mental Disorders
Mood Disorders

Hydrocortisone acetate
Depressive Disorder, Major
Depressive Disorder
Behavioral Symptoms

ClinicalTrials.gov processed this record on January 16, 2009