Home
Search
Study Topics
Glossary
|
|
|
|
|
|
Sponsors and Collaborators: |
Allegheny General Hospital Merck |
---|---|
Information provided by: | Allegheny General Hospital |
ClinicalTrials.gov Identifier: | NCT00189475 |
Assesses the efficacy of treatment with montelukast 10 mg PO QD x 5 days versus placebo for the treatment of viral-induced upper respiratory infection in healthy adults aged 18-50 years.
Condition | Intervention | Phase |
---|---|---|
Upper Respiratory Infection |
Drug: Montelukast |
Phase IV |
Study Type: | Interventional |
Study Design: | Randomized, Double-Blind, Placebo Control, Parallel Assignment |
Official Title: | A Pilot Study to Evaluate the Potential of Montelukast to Prevent the Development of Nasal Symptomatology During Natural Viral Upper Respiratory Infections |
This is a randomized double-blinded placebo controlled trial to assess the efficacy of treatment with montelukast 10 mg PO QD x 5 days versus placebo for the treatment of viral-induced upper respiratory infection in healthy adults aged 18-50 years. All subjects complete daily assessments of cold symptoms, nasal clearance rates and secretion rates during each day of the study. Phlebotomy is performed once for the determination of cytokine genotyping and allergy skin testing is performed once for the assessment of atopy.
Ages Eligible for Study: | 18 Years to 50 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
United States, Pennsylvania | |
Allegheny General Hospital | |
Pittsburgh, Pennsylvania, United States, 15212 |
Principal Investigator: | Deborah Gentile, MD | Allegheny General Hospital |
Study ID Numbers: | RC - 3559 |
Study First Received: | September 13, 2005 |
Last Updated: | July 27, 2007 |
ClinicalTrials.gov Identifier: | NCT00189475 |
Health Authority: | United States: Institutional Review Board |
Cold Upper Respiratory Infection |
Montelukast Virus Diseases Respiratory Tract Diseases Respiratory Tract Infections |
Common Cold Picornaviridae Infections Leukotriene Antagonists |
Respiratory System Agents Communicable Diseases RNA Virus Infections Therapeutic Uses Hormone Antagonists |
Physiological Effects of Drugs Hormones, Hormone Substitutes, and Hormone Antagonists Anti-Asthmatic Agents Infection Pharmacologic Actions |