Home
Search
Study Topics
Glossary
|
|
|
|
|
|
Sponsors and Collaborators: |
University of Michigan Arthritis Foundation |
---|---|
Information provided by: | University of Michigan |
ClinicalTrials.gov Identifier: | NCT00189124 |
The purpose of this study is to evaluate the effect of DHEA on endothelial dysfunction in patients with systemic lupus by measuring:
HYPOTHESIS: Dehydroepiandrosterone (DHEA) administration in premenopausal women with SLE modifies cardiovascular risk by improving vascular endothelial function and other biomarkers associated with cardiovascular heart disease.
Condition | Intervention | Phase |
---|---|---|
Systemic Lupus Erythematosus |
Drug: Dehydroepiandrosterone (DHEA) |
Phase II Phase III |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double-Blind, Placebo Control, Crossover Assignment, Safety/Efficacy Study |
Official Title: | Does DHEA Improve Endothelial Dysfunction and Other Cardiovascular Risk Factors in Premenopausal Women With Systemic Lupus? |
Estimated Enrollment: | 20 |
Study Start Date: | June 2001 |
Estimated Study Completion Date: | October 2006 |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Wendy Marder, MD | (734) 936-1166 | wmarder@umich.edu |
United States, Michigan | |
University of Michigan | Recruiting |
Ann Arbor, Michigan, United States, 48109 | |
Contact: Wendy Marder, MD 734-936-1166 wmarder@umich.edu | |
Principal Investigator: Wendy Marder, MD |
Principal Investigator: | Wendy Marder, MD | University of Michigan |
Study ID Numbers: | 2001-0822, GCRC# 1883 |
Study First Received: | September 13, 2005 |
Last Updated: | February 22, 2006 |
ClinicalTrials.gov Identifier: | NCT00189124 |
Health Authority: | United States: Food and Drug Administration |
Systemic Lupus Erythematosus Dehydroepiandrosterone (DHEA) DHEA SLE Lupus |
Arterial Occlusive Diseases Coronary Disease Autoimmune Diseases Heart Diseases Lupus Erythematosus, Systemic Myocardial Ischemia |
Connective Tissue Diseases Vascular Diseases Dehydroepiandrosterone Arteriosclerosis Ischemia Coronary Artery Disease |
Immunologic Factors Immune System Diseases Physiological Effects of Drugs |
Adjuvants, Immunologic Cardiovascular Diseases Pharmacologic Actions |