Follow up of Autoantibodies in Active Tuberculosis

This study is not yet open for participant recruitment.

Verified by Tel-Aviv Sourasky Medical Center, October 2007

Sponsored by:	Tel-Aviv Sourasky Medical Center
Information provided by:	Tel-Aviv Sourasky Medical Center
ClinicalTrials.gov Identifier:	NCT00551226

Purpose

We have previoulsy shown that patients with active Tuberculosis develop a wide array of autoantibodies including rheumatoid factor, anti-CCP, Antinuclear facyor and anti Sm antibodies. The purpose of this study is to evaluate whether the level of autoantibodies decrease after treatment aganist tuberculosis.

Condition
Tuberculosis

MedlinePlus related topics: Tuberculosis

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	Follow up of Autoantibodies in Active Tuberculosis

Further study details as provided by Tel-Aviv Sourasky Medical Center:

Primary Outcome Measures:

Follow up after levels of autoantibodies [ Time Frame: 1 year ]

Biospecimen Retention: Samples Without DNA

Biospecimen Description:

Serum of patients

Estimated Enrollment:	50
Study Start Date:	November 2007
Estimated Study Completion Date:	November 2008

Groups/Cohorts
1 Patients with tuberculosis
2 Healthy controls

Eligibility

Ages Eligible for Study:	18 Years to 90 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

Patients diagnosed with active tuberculosis who are currently receiving anti tuberculosis drugs

Criteria

Inclusion Criteria:

Active Tuberculosis treated

Exclusion Criteria:

None

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00551226

Contacts

Contact: Ori Elkayam, M.D

97236973668

oribe14@netvision.net.il

Locations

Israel
Tel Aviv Medical Center
Tel Aviv, Israel, 64239

Sponsors and Collaborators

Tel-Aviv Sourasky Medical Center

Investigators

Principal Investigator:

Ori Elkayam, M.D

Tel Aviv Medical Center

More Information

Study ID Numbers:	314-07
Study First Received:	October 27, 2007
Last Updated:	October 29, 2007
ClinicalTrials.gov Identifier:	NCT00551226
Health Authority:	Israel: Ministry of Health

Keywords provided by Tel-Aviv Sourasky Medical Center:

TB
Patients with tuberculosis

Study placed in the following topic categories:

Bacterial Infections
Gram-Positive Bacterial Infections
Autoantibodies
Mycobacterium Infections
Tuberculosis

Additional relevant MeSH terms:

Immunologic Factors
Physiological Effects of Drugs
Pharmacologic Actions
Actinomycetales Infections

ClinicalTrials.gov processed this record on January 15, 2009