3 Screen Electronic Alert - Full Text View

Sponsors and Collaborators:	Brigham and Women's Hospital Eisai Inc.
Information provided by:	Brigham and Women's Hospital
ClinicalTrials.gov Identifier:	NCT00550082

Purpose

Evaluation of physician responses to BICS-Clinical Information 3-screen alerts that informs the clinician that his/her patient may be eligible for thromboprophylaxis.

Condition
Deep Vein Thrombosis Pulmonary Embolism Cancer

MedlinePlus related topics: Deep Vein Thrombosis Pulmonary Embolism

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	Multi-Screen Electronic Alert for Venous Thromboembolism Prevention

Further study details as provided by Brigham and Women's Hospital:

Primary Outcome Measures:

Venous Thromboembolism and Bleeding Events [ Time Frame: 90 Days ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Re-hospitalization [ Time Frame: 90 Days ] [ Designated as safety issue: No ]
Mortality [ Time Frame: 30 Days ] [ Designated as safety issue: No ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	2500
Study Start Date:	July 2007
Estimated Study Completion Date:	June 2008

Show Detailed Description

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Hospitalized patients at Brigham and Women's Hospital from medical and surgical services who are 18 yrs old or older and are at a moderate to high risk for venous thromboembolism (VTE)

Criteria

Inclusion Criteria:

Hospitalized patients at Brigham and Women's Hospital from medical and surgical services who are 18 yrs old or older and are at a moderate to high risk for venous thromboembolism (VTE)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00550082

Contacts

Contact: Samuel Z Goldhaber, MD	617-732-6984	sgoldhaber@partners.org
Contact: Karen Fiumara, PharmD	617-732-7857	kfiumara@partners.org

Locations

United States, Massachusetts
Brigham and Women's Hospital	Recruiting
Boston, Massachusetts, United States, 02115
Contact: Samuel Z Goldhaber, MD 617-732-6984 sgoldhaber@partners.org
Contact: Karen Fiumara, MD 617732-7857 kfiumara@partners.org
Principal Investigator: Samuel Z Goldhaber, MD
Sub-Investigator: Karen Fiumara, PharmD
Sub-Investigator: John Fanikos, RPh, MBA
Sub-Investigator: Steven Baroletti, PharmD, MBA
Sub-Investigator: Chiara Piovella, MD
Sub-Investigator: Matthew Labreche
Sub-Investigator: Matthew Niles

Sponsors and Collaborators

Brigham and Women's Hospital

Eisai Inc.

Investigators

Principal Investigator:

Samuel Z Goldhaber, MD

Brigham and Women's Hospital

More Information

North American Thrombosis Forum (NATF) This link exits the ClinicalTrials.gov site

Publications:

Parasuraman S, Goldhaber SZ. Venous thromboembolism in children. Circulation. 2006 Jan 17;113(2):e12-6. Review. No abstract available.

Piazza G, Goldhaber SZ. Acute pulmonary embolism: part II: treatment and prophylaxis. Circulation. 2006 Jul 18;114(3):e42-7. Review. No abstract available.

Piazza G, Goldhaber SZ. Acute pulmonary embolism: part I: epidemiology and diagnosis. Circulation. 2006 Jul 11;114(2):e28-32. No abstract available.

Geerts WH, Pineo GF, Heit JA, Bergqvist D, Lassen MR, Colwell CW, Ray JG. Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004 Sep;126(3 Suppl):338S-400S. Review.

Paterno MD, Cina JL, Goldhaber SZ, Kucher N. Preventing DVT and PE in hospitalized patients: improving a successful electronic alert. AMIA Annu Symp Proc. 2006;:1058.

Kucher N, Goldhaber SZ. Risk stratification of acute pulmonary embolism. Semin Thromb Hemost. 2006 Nov;32(8):838-47. Review.

Kucher N, Koo S, Quiroz R, Cooper JM, Paterno MD, Soukonnikov B, Goldhaber SZ. Electronic alerts to prevent venous thromboembolism among hospitalized patients. N Engl J Med. 2005 Mar 10;352(10):969-77.

Goldhaber SZ, Dunn K, MacDougall RC. New onset of venous thromboembolism among hospitalized patients at Brigham and Women's Hospital is caused more often by prophylaxis failure than by withholding treatment. Chest. 2000 Dec;118(6):1680-4.

Goldhaber SZ, Turpie AG. Prevention of venous thromboembolism among hospitalized medical patients. Circulation. 2005 Jan 4;111(1):e1-3. Review. No abstract available.

Goldhaber SZ, Tapson VF; DVT FREE Steering Committee. A prospective registry of 5,451 patients with ultrasound-confirmed deep vein thrombosis. Am J Cardiol. 2004 Jan 15;93(2):259-62.

Cushman M, Tsai AW, White RH, Heckbert SR, Rosamond WD, Enright P, Folsom AR. Deep vein thrombosis and pulmonary embolism in two cohorts: the longitudinal investigation of thromboembolism etiology. Am J Med. 2004 Jul 1;117(1):19-25.

Anderson FA Jr, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, Forcier A, Dalen JE. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med. 1991 May;151(5):933-8.

Responsible Party:	Brigham and Women's Hospital ( Samuel Z. Goldhaber, MD )
Study ID Numbers:	2006-P-002346
Study First Received:	October 24, 2007
Last Updated:	February 12, 2008
ClinicalTrials.gov Identifier:	NCT00550082
Health Authority:	United States: Institutional Review Board

Keywords provided by Brigham and Women's Hospital:

Anticoagulation
High-Risk
Deep Vein Thrombosis
Pulmonary Embolism
Surgery

Study placed in the following topic categories:

Embolism and Thrombosis
Pulmonary Embolism
Respiratory Tract Diseases
Embolism
Lung Diseases

Vascular Diseases
Venous Thrombosis
Venous Thromboembolism
Thromboembolism
Thrombosis

Additional relevant MeSH terms:

Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 15, 2009