Cortical Interneurons and Pyramidal Cells in Neurovascular Coupling Responses to Afferent Pathway Simulation

 


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Air date: Monday, January 08, 2007, 12:00:00 PM
Category: Neuroscience
Runtime: 75 minutes
NLM Title: Cortical interneurons and pyramidal cells in neurovascular coupling responses to afferent pathway simulation [electronic resource] / Edith Hamel.
Author: Hamel, E.
National Institutes of Health (U.S.)
Publisher: [Bethesda, Md. : National Institutes of Health, 2007]
Abstract: (CIT): Dr. Hamel and her colleagues study neurons and glial cells in the brain can locally influence the brain's blood supply. The dysfunction/degeneration of specific populations of cells may have dramatic repercussions on the local regulation of blood flow. Tract tracing studies and immunocytochemistry are used to study the anatomical relationships between neurons and blood vessels as well as the cellular localization, molecular composition, and pharmacological properties of receptors mediating vasomotor responses. The goal of this work is to understand how brain neurons control local cerebral perfusion and how this relationship is altered in pathological states like Alzheimer's Disease and migraine headache. Ultimately, new drugs could be developed to preserve a normal blood supply to the brain in the absence of neurogenic regulation. NIH Neuroscience Seminar Series.
Subjects: Afferent Pathways--physiology
Brain--blood supply
Cerebrovascular Circulation
Interneurons--physiology
Pyramidal Cells--physiology
Vasomotor System--physiology
Publication Types: Government Publications
Lectures
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NLM Classification: WL 302
NLM ID: 101298612
CIT File ID: 13570
CIT Live ID: 5230
Permanent link: http://videocast.nih.gov/launch.asp?13570

 

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