Home
Search
Study Topics
Glossary
|
|
|
|
|
|
Sponsored by: |
Dresden University of Technology |
---|---|
Information provided by: | Dresden University of Technology |
ClinicalTrials.gov Identifier: | NCT00678756 |
Exploration of antipsoriatic effects of UVB-therapy +/- CYP-inhibitor Ketokonazol on affected psoriatic skin
Condition | Intervention | Phase |
---|---|---|
Psoriasis Vulgaris |
Drug: Ketokonazol 2% cream Radiation: UVB-radiation 311nm |
Phase II |
Study Type: | Interventional |
Study Design: | Treatment, Non-Randomized, Open Label, Active Control, Parallel Assignment, Safety Study |
Official Title: | Investigation of Antipsoriatic Effects of UVB-Induced Synthesis of 1alpha, 25-Dihydroxyvitamin D3 (1alpha, 25(OH)2D3, Calcitriol)in Keratinocytes of Psoriatic Skin, Using Cytochrom-P(CYP)Inhibitor Ketokonazol |
Estimated Enrollment: | 12 |
Study Start Date: | March 2008 |
Estimated Study Completion Date: | December 2009 |
Estimated Primary Completion Date: | October 2009 (Final data collection date for primary outcome measure) |
Ages Eligible for Study: | 18 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Gottfried Wozel, Prof. Dr. med | 0049-351-458 | katharina.bluemlein@mailbox.tu-dresden.de |
Germany | |
Department of Dermatology, Medical Faculty, TU Dresden | Recruiting |
Dresden, Germany, 01307 | |
Contact: Gottfried Wozel, Prof. Dr.med. 0049-351-458 ext 2007 katharina.bluemlein@mailbox.tu-dresden.de | |
Principal Investigator: Gottfried Wozel, Prof. Dr.med | |
Sub-Investigator: Sophia Deter, cand.med. |
Principal Investigator: | Gottfried Wozel, Prof. Dr.med | Department of Dermatology, Medical Faculty, Technical University Dresden, Germany |
Responsible Party: | Technical University Dresden, Department of Dermatology ( Prof. Dr. med. Gottfried Wozel ) |
Study ID Numbers: | TUD-VITAKET |
Study First Received: | May 14, 2008 |
Last Updated: | May 14, 2008 |
ClinicalTrials.gov Identifier: | NCT00678756 |
Health Authority: | Germany: Federal Institute for Drugs and Medical Devices |
Psoriasis vulgaris, vitamin D, UVB-phototherapy, ketokonazol, Optical Coherence Tomography, local PASI, Nizoral |
Calcium, Dietary Vitamin D Skin Diseases Psoriasis Ergocalciferols |
Ketoconazole Dihydroxycholecalciferols Skin Diseases, Papulosquamous Calcitriol |
Membrane Transport Modulators Molecular Mechanisms of Pharmacological Action Therapeutic Uses Growth Substances Vitamins Calcium Channel Agonists |
Physiological Effects of Drugs Vasoconstrictor Agents Bone Density Conservation Agents Cardiovascular Agents Micronutrients Pharmacologic Actions |