Color Flow Doppler Ultrasound in Subclinical Thyroid Dysfunction

This study is not yet open for participant recruitment.

Verified by HaEmek Medical Center, Israel, February 2007

Sponsored by:	HaEmek Medical Center, Israel
Information provided by:	HaEmek Medical Center, Israel
ClinicalTrials.gov Identifier:	NCT00437931

Purpose

Overt hyperthyroidism and hypothyroidism are associated with inverted hemodynamic changes.Regional blood flow disturbances (including intrathyroidal) were also reported in these thyroid disorders. The purpose of this study is to investigate the thyroid vascularity and blood flow by Color Flow Doppler Sonography in patients with subclinical thyroid dysfunction

Condition
Subclinical Hypothyroidism Hyperthyroidism Thyroid Dysfunction

MedlinePlus related topics: Ultrasound

Drug Information available for: Thyroid

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening, Cross-Sectional, Case Control, Prospective Study

Further study details as provided by HaEmek Medical Center, Israel:

Estimated Enrollment:	60
Study Start Date:	February 2007
Estimated Study Completion Date:	February 2008

Detailed Description:

Color Flow Doppler Sonography (CFDS) has become in the last years an increasing procedure to assess the thyroid blood flow. Previous studies showed specific changes of thyroid blood flow in hyperthyroidism, Hashimoto's thyroiditis and thyroid nodules when investigated by CFDS. Subclinical hyperthyroidism and hypothyroidism are common laboratory findings, defined by normal thyroid hormones concentrations along with ,respectively,decreased or increase Thyroid stimulating hormone (TSH) level. We purpose to investigate thyroid vascularity by CFDS in patients with subclinical hyperthyroidism or hypothyroidism and compared them with euthyroid patients.

Eligibility

Ages Eligible for Study:	18 Years to 75 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

patients with subclinical hypothyroidism or hyperthyroidism
patients with thyroid nodules and normal thyroid function

Exclusion Criteria:

patients who are taking thyroxine, antithyroid drugs, lithium or amiodarone
patients who had thyroid surgery or radioiodine therapy
patients with NYHA class 3 or 4 heart failure

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00437931

Contacts

Contact: Avraham Ishay, MD	972-4-6495556	ishay_av@clalit.org.il
Contact: Rafael Luboshitzky, MD	972-4-5495553	luboshitzky_r@clalit.org.il

Locations

Israel
Haemek Medical Center, Department of Radiology
Afula, Israel, 18101

Sponsors and Collaborators

HaEmek Medical Center, Israel

Investigators

Principal Investigator:	Avraham Ishay, MD	Haemek Medical Center, Endocrine Institute, Afula, Israel
Study Chair:	Leonid Chervinsky	Haemek Medical Center, Department of Radiology, Afula , Israel
Study Chair:	Rafael Luboshitzky, MD	Haemek Medical Center, Endocrine Institute, Afula, Israel

More Information

Study ID Numbers:	006-07-EMC
Study First Received:	February 19, 2007
Last Updated:	February 19, 2007
ClinicalTrials.gov Identifier:	NCT00437931
Health Authority:	Israel: Ethics Commission

Keywords provided by HaEmek Medical Center, Israel:

hypothyroidism
hyperthyroidism
thyroid dysfunction
ultrasound
doppler

Study placed in the following topic categories:

Endocrine System Diseases
Hypothyroidism
Endocrinopathy
Thyroid Diseases
Hyperthyroidism

ClinicalTrials.gov processed this record on January 15, 2009