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Sponsored by: |
Hospital University Vall d'Hebron |
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Information provided by: | Hospital University Vall d'Hebron |
ClinicalTrials.gov Identifier: | NCT00437177 |
OH dependence is associated with DA receptor changes. Both, the apomorphine test and the D2Rec SPECt are usefull for monitoring DA receptor status. We aimed at studying whether DA receptor hypofunction, assessed by means of the apomorphine test and the D2Rec SPECT, is a marker of relapse in detoxified OH dependents patients.
Condition | Intervention | Phase |
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Alcoholism |
Drug: apomorphine Drug: [(123)I] iodobenzamide |
Phase II |
Study Type: | Interventional |
Study Design: | Basic Science, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment |
Official Title: | Relationship Between D2 Receptors SPECT and the Apomorphine Test in Patients With OH Dependence: Predictive Value for Relapse |
Estimated Enrollment: | 50 |
Study Start Date: | January 2007 |
Estimated Study Completion Date: | December 2008 |
Estimated Primary Completion Date: | December 2008 (Final data collection date for primary outcome measure) |
Ages Eligible for Study: | 25 Years to 60 Years |
Genders Eligible for Study: | Male |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Miquel Casas, Prof. | mcasas@vhebron.net | |
Contact: Xavier Castells, Prof | xcc@icf.uab.cat |
Spain, Catalonia | |
Psychiatry Service, Hospital Universitari Vall d'Hebron | Recruiting |
Barcelona, Catalonia, Spain, 08036 | |
Contact: Miquel Casas, Prof mcasas@vhebron.net | |
Contact: Xavier Castells xcc@icf.uab.cat | |
Principal Investigator: Miquel Casas, Prof |
Principal Investigator: | Miquel Casas, Prof | Psychiatry Service, Hospital Universitari Vall d'Hebron |
Responsible Party: | Servei de Psiquiatria. Hospital Universitari Vall d'Hebron ( m ) |
Study ID Numbers: | OH SPECT APO, EudraCT: 2004-001893-24 |
Study First Received: | February 16, 2007 |
Last Updated: | June 4, 2008 |
ClinicalTrials.gov Identifier: | NCT00437177 |
Health Authority: | Spain: Spanish Agency of Medicines |
alcoholism apomorphine iodobenzamide |
imaging spect relapse |
Dopamine Mental Disorders Alcoholism Substance-Related Disorders |
Disorders of Environmental Origin Alcohol-Related Disorders Apomorphine |
Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Anti-Dyskinesia Agents Therapeutic Uses Physiological Effects of Drugs |
Antiparkinson Agents Dopamine Agents Dopamine Agonists Central Nervous System Agents Pharmacologic Actions |