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PRO 140



Drug Class: Entry and Fusion Inhibitors

PRO 140 is a type of medicine called an entry inhibitor. Entry inhibitors work by blocking the entry of HIV into human cells.


HIV/AIDS-Related Uses


PRO 140 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials. It is being studied for the treatment of HIV infection. This medicine does not cure or prevent HIV infection or AIDS and does not reduce the risk of passing the virus to other people.


Dosage Form/Administration


PRO 140 comes in liquid form that is given by intravenous infusion into a vein. Future studies administering PRO 140 by subcutaneous injection are planned.


Recommended Daily Dose


Several doses of PRO 140 from 0.1 to 5 mg/kg have been studied in clinical trials.


Contraindications


Individuals should tell a doctor about any medical problems before taking this medicine.


Possible Side Effects


Along with its desired effects, PRO 140 may cause some unwanted effects. No major side effects have been reported in studies so far.


Drug and Food Interactions


A doctor should be notified of any other medications being taken, including prescription, nonprescription (over-the-counter), or herbal medications.


Clinical Trials


Click here to search ClinicalTrials.gov for trials that use PRO 140.


Manufacturer Information


PRO 140
  Progenics Pharmaceuticals, Inc.
  777 Old Saw Mill Road
  Tarrytown,  NY  10591
    



Updated October 16, 2007