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Tenofovir
te-NOE-fo-veer   Audio
Drug Class: Microbicides
Tenofovir gel, also known as PMPA gel, is a type of medicine called a microbicide. Microbicides are substances that protect the body from infection by microorganisms such as bacteria, viruses, and fungi. Microbicides work by either destroying the microbes or preventing them from establishing an infection.

HIV/AIDS-Related Uses
Tenofovir gel is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials. It is being studied for the prevention of HIV transmission. This medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing the virus to other people.

Dosage Form/Administration
Tenofovir gel comes in topical gel form and is applied vaginally.

Recommended Daily Dose
Different strengths and doses of tenofovir gel are being studied. Tenofovir 0.3% and 1% gels are being studied for once-daily, twice-daily, or as needed use.

Contraindications
Individuals should tell a doctor about any medical problems before taking this medicine.

Possible Side Effects
Along with its desired effects, tenofovir gel may cause some unwanted effects. Most effects have been mild and limited to the application area. Although not all of these effects are known, vaginal itching, redness, and discharge have been reported.


Drug and Food Interactions
A doctor should be notified of any other medications being taken, including prescription, nonprescription (over-the-counter), or herbal medications.

Clinical Trials
Click here to search ClinicalTrials.gov for trials that use Tenofovir.

Manufacturer Information
Tenofovir
  Gilead Sciences Inc
  333 Lakeside Dr
  Foster City,  CA  94404
  (800) 445-3235
    
Updated June 4, 2008