Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea Before and After Treatment With CPAP.

This study has been completed.

Sponsored by:	Holstebro Hospital
Information provided by:	Holstebro Hospital
ClinicalTrials.gov Identifier:	NCT00360659

Purpose

We wanted to test the hypothesis that treatment with continuous positive airway pressure reduces nocturnal hypoxia and thereby affecting levels of vasoactive hormones leading to a fall in blood pressure patients with obstructive sleep apnea.

Condition	Intervention	Phase
Obstructive Sleep Apnea	Device: Continuous Positive Airway Pressure	Phase IV

MedlinePlus related topics: Sleep Apnea

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Non-Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study

Further study details as provided by Holstebro Hospital:

Estimated Enrollment:	50
Study Start Date:	February 2004
Estimated Study Completion Date:	February 2005

Eligibility

Ages Eligible for Study:	20 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Age between 20 and 65 years
Obstructive sleep apnea
Hypertension or normal blood pressure

Exclusion Criteria:

Drug or alcohol abuse
Pregnancy
History or clinical signs of disease in the heart, lungs, brain,liver, kidneys or endocrine organs
Diabetes

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00360659

Locations

Denmark, Ringkoebing County
Department of Medicine, Holstebro Hospital
Holstebro, Ringkoebing County, Denmark, 7500

Sponsors and Collaborators

Holstebro Hospital

Investigators

Study Chair:

Erling B Pedersen, Professor

Holstebro Hospital

More Information

Responsible Party:	Department of Medical Research, Holstebro Hospital ( Pia H Gjørup )
Study ID Numbers:	MED.RES.HOS.2004.02.PHH
Study First Received:	August 3, 2006
Last Updated:	April 17, 2008
ClinicalTrials.gov Identifier:	NCT00360659
Health Authority:	Denmark: The Danish National Committee on Biomedical Research Ethics

Keywords provided by Holstebro Hospital:

Obstructive sleep Apnea
Hypertension
Vasoactive hormones

Study placed in the following topic categories:

Signs and Symptoms
Sleep Apnea Syndromes
Respiratory Tract Diseases
Apnea
Respiration Disorders
Sleep Apnea, Obstructive

Dyssomnias
Sleep Disorders
Signs and Symptoms, Respiratory
Sleep Disorders, Intrinsic
Hypertension

Additional relevant MeSH terms:

Nervous System Diseases

ClinicalTrials.gov processed this record on January 15, 2009