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Sponsors and Collaborators: |
Hawler Medical University HAWLER Maternity Hospital |
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Information provided by: | Hawler Medical University |
ClinicalTrials.gov Identifier: | NCT00797693 |
The purpose of this study is to determine whether oral versus vaginal misoprostol is effective in termination of first trimester missed abortion and to compare between two different routes.
Condition | Intervention |
---|---|
Miscarriage |
Drug: Misoprostol ( Cytotec) 200 microgram a tablet |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study |
Official Title: | Oral Versus Vaginal Misoprostol as Cervical Ripening Agent Prior to Surgical Termination of First Trimester Missed Abortions in Hawler Maternity Teaching Hospital in Erbil/Iraq |
Enrollment: | 100 |
Study Start Date: | January 2008 |
Study Completion Date: | May 2008 |
Primary Completion Date: | May 2008 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
---|---|
Vaginal Misoprostol: Experimental
A drug is given vaginally and to compare this with an oral administration of the same drug to find it is effect on it is effect on the cervix
|
Drug: Misoprostol ( Cytotec) 200 microgram a tablet
In this study, two arms we put under study ... and to find how far a single drug, Misoprostol, is effective to have changes on the cervix.
|
Oral Misoprostol: Experimental
A drug is given vaginally and to compare this with an oral administration of the same drug to find it is effect on it is effect on the cervix
|
Drug: Misoprostol ( Cytotec) 200 microgram a tablet
In this study, two arms we put under study ... and to find how far a single drug, Misoprostol, is effective to have changes on the cervix.
|
Objective: To compare the effectiveness of oral versus vaginal misoprostol prior to surgical termination of first trimester missed abortion as cervical priming agent , the difference of cervical dilatation immediately prior to operation , the duration of operation and side effects between two treatment groups.
Design: This study was conducted as randomised study.
Setting: Maternity Teaching Hospital in Hawler/ Kurdistan/ Iraq.
Population: Over a period of six months from the first of January to the thirtieth of June, 2008, one hundred women were included in this study. They were cases of first trimester abortion (6-12 weeks).
Method: Patients were randomly selected for the type of treatment they received. The first group (oral) were assigned to receive 400 micrograms of misoprostol orally as preoperative cervical priming agent, where as the second group (vaginal) were allocated to have treatment either with vaginal misoprostol to receive 400 micrograms vaginally.
Main outcome measure: Oral versus vaginal misoprostol as cervical ripening agent prior to termination of first trimester missed abortion.
Keywords: First trimester, missed abortion, misoprostol, cervical ripening, oral, vaginal.
Ages Eligible for Study: | 20 Years to 35 Years |
Genders Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Responsible Party: | Hawler Medical University ( Scientific Committe ) |
Study ID Numbers: | 324/2 |
Study First Received: | November 21, 2008 |
Last Updated: | November 24, 2008 |
ClinicalTrials.gov Identifier: | NCT00797693 |
Health Authority: | IRAQ: HAWLER COLLEGE OF MEDICINE |
First trimester missed abortion misoprostol cervical ripening |
oral vaginal first trimester missed abortion |
Pregnancy Complications Abortion, Missed Misoprostol Abortion, Spontaneous |
Oxytocics Therapeutic Uses Anti-Ulcer Agents Physiological Effects of Drugs Abortifacient Agents |
Gastrointestinal Agents Reproductive Control Agents Abortifacient Agents, Nonsteroidal Pharmacologic Actions |