Genetics of Symptomatology and Treatment Response in Psychotic Major Depression

This study is currently recruiting participants.

Verified by Stanford University, June 2008

Sponsored by:	Stanford University
Information provided by:	Stanford University
ClinicalTrials.gov Identifier:	NCT00691535

Purpose

We hope to learn more about the biology of psychiatric illness with the hope of improving the diagnosis and treatment of such psychiatric conditions as major depression.

Condition
Psychotic Disorders Depressive Disorder Depressive Disorder, Major

MedlinePlus related topics: Depression Psychotic Disorders

U.S. FDA Resources

Study Type:	Observational
Official Title:	Association of BDNF, COMT, MDRI, CRH, CRF, and GC Receptor Genetic Polymorphisms With Symptomatology and Treatment Response in Psychotic Major Depression

Further study details as provided by Stanford University:

Estimated Enrollment:	500
Study Start Date:	October 2003

Detailed Description:

From the blood sample you donate, the researchers will obtain DNA. This DNA will be used to search for DNA markers related to the underlying biology of psychiatric illness and how this might explain the symptoms of these disorders. Research using DNA is an important way to try to understand human disease and/or the role genes play in disease. In effect, part of your blood sample will be used to attempt to understand how genetic factors contribute to the symptoms of such psychiatric conditions as major depression.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

You are currently experiencing symptoms that are consistent with an episode of major depression without symptoms of psychosis (such as hallucinations, delusions or disorder of thought process), or
You are currently experiencing symptoms that are consistent with an episode of major depression with symptoms of psychosis (such as hallucinations, delusions or disorder of thought process), or
You have been diagnosed with either schizophrenia or schizoaffective disorder, or
You are a volunteer without a history of psychiatric illness (a healthy control subject).

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00691535

Contacts

Contact: Gregory H Cohen, MSW

(650) 723-3305

ghcohen@stanford.edu

Locations

United States, California
Stanford University School of Medicine	Recruiting
Stanford, California, United States, 94305
Contact: Gregory H Cohen, MSW 650-723-3305 ghcohen@stanford.edu
Principal Investigator: Anna Lembke
Sub-Investigator: Alan Schatzberg
Sub-Investigator: Greer Murphy

Sponsors and Collaborators

Stanford University

Investigators

Sub-Investigator:

Alan Schatzberg

Stanford University

More Information

Study ID Numbers:	SU-05132008-1160
Study First Received:	June 3, 2008
Last Updated:	June 4, 2008
ClinicalTrials.gov Identifier:	NCT00691535
Health Authority:	USA:Institutional Review Board

Study placed in the following topic categories:

Schizophrenia
Depression
Mental Disorders
Mood Disorders
Psychotic Disorders

Depressive Disorder, Major
Depressive Disorder
Schizophrenia and Disorders with Psychotic Features
Behavioral Symptoms

Additional relevant MeSH terms:

Pathologic Processes
Disease

ClinicalTrials.gov processed this record on January 15, 2009