A Validation Study of a New System for Measuring the End Expiratory Lung Volume During Mechanical Ventilation - Full Text View

Sponsored by:	Policlinico Hospital
Information provided by:	Policlinico Hospital
ClinicalTrials.gov Identifier:	NCT00405002

Purpose

In this study the investigators aim to evaluate a new system dedicated to estimate the end expiratory lung volume, by measuring the VO2-VCO2, during mechanical ventilation compared to the helium dilution technique and the computed tomography (CT) scan.

Condition	Intervention
Respiratory Failure	Procedure: Helium dilution technique, lung CT scan

MedlinePlus related topics: CT Scans Nuclear Scans

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	A Validation Study of a New System for Measuring the End Expiratory Lung Volume During Mechanical Ventilation Acute in Intubated Patients

Further study details as provided by Policlinico Hospital:

Biospecimen Retention: None Retained

Biospecimen Description:

Enrollment:	30
Study Start Date:	November 2006
Study Completion Date:	July 2008
Primary Completion Date:	July 2008 (Final data collection date for primary outcome measure)

Groups/Cohorts	Assigned Interventions
1 ALI/ARDS patients	Procedure: Helium dilution technique, lung CT scan Helium dilution technique and lung CT scan

Detailed Description:

In this study we aimed to evaluate a new system dedicated to estimate the end expiratory lung volume, by measuring the VO2-VCO2, during mechanical ventilation compared to the Helium dilution technique and the CT scan. We will compare the data considering the CT scan data as the gold standard.

Eligibility

Ages Eligible for Study:	18 Years to 85 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

ALI/ARDS patients

Criteria

Inclusion Criteria:

Adult intubated subjects

Exclusion Criteria:

Barotrauma

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00405002

Locations

Italy
Policlinico Hospital
Milano, Italy

Sponsors and Collaborators

Policlinico Hospital

Investigators

Principal Investigator:

Davide Chiumello, MD

Policlinico Hospital

More Information

Responsible Party:	Policlinico Hospital ( Davide Chiumello )
Study ID Numbers:	101020
Study First Received:	November 27, 2006
Last Updated:	September 24, 2008
ClinicalTrials.gov Identifier:	NCT00405002
Health Authority:	Italy: Ministry of Health

Keywords provided by Policlinico Hospital:

Acute respiratory failure

Study placed in the following topic categories:

Respiratory Insufficiency
Respiratory Tract Diseases
Respiration Disorders

ClinicalTrials.gov processed this record on January 14, 2009