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| Sponsored by: |
Bispebjerg Hospital |
|---|---|
| Information provided by: | Bispebjerg Hospital |
| ClinicalTrials.gov Identifier: | NCT00404469 |
Purpose
We will investigate the effect of peritendinous corticosteroid injections, eccentric training and heavy resistance training in male patellar tendinopathy patients. The purpose is to compare the clinical effect of these three treatments in a randomised controlled trial. Also we wish to investigate the treatment mechanisms responsible for the effectiveness of the three treatments.
| Condition | Intervention |
|---|---|
|
Patellar Tendinopathy / Jumpers Knee |
Procedure: peritendinous corticosteroid injections Procedure: eccentric decline squat training Procedure: heavy slow resistance training |
| Study Type: | Interventional |
| Study Design: | Basic Science, Randomized, Single Blind (Investigator), Active Control, Parallel Assignment |
| Official Title: | Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy |
| Enrollment: | 39 |
| Study Start Date: | March 2006 |
| Study Completion Date: | November 2007 |
| Arms | Assigned Interventions |
|---|---|
|
CORT: Active Comparator
Peritendinous corticosteroid injections at 0 and 4 weeks. 12 weeks total
|
Procedure: peritendinous corticosteroid injections
1 ml of40mg/ml methylprednisolone acetate at 0 and 4 weeks. 2 week observational
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ECC: Experimental
12 weeks of eccentric unilateral decline squats
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Procedure: eccentric decline squat training
eccentric decline unilateral squats performed twice daily. for 12 weeks
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HSR: Experimental
Heavy slow resistance training. 3/week. 12 weeks
|
Procedure: heavy slow resistance training
Heavy slow resistance training for knee extensors. 3/week. total of 12 weeks
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3 interventions groups as described above (n=13 in each group) 12 weeks intervention period. Clinical assessments before and after intervention: VAS, VISA, Tendon thickness, Doppler us activity.
Before and after intervention tendon biopsies will be taken and analyzed for crosslinks and fibril diameter. Also tendon mechanical properties will be measured. Tendon and muscle structural properties will be measured with MRI.
Treatment satisfaction will be stated after intervention period.
Eligibility| Ages Eligible for Study: | 18 Years to 55 Years |
| Genders Eligible for Study: | Male |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Denmark | |
| Institute of Sports Medicine Copenhagen. Dept 8 1st floor. Bispebjerg Hospital | |
| Copenhagen, Denmark, 2400 | |
| Principal Investigator: | Mads Kongsgaard, PhD., MSc. | Institute of Sports Medicine Copenhagen |
More Information
| Study ID Numbers: | Patellar tendinopathy |
| Study First Received: | November 27, 2006 |
| Last Updated: | May 21, 2008 |
| ClinicalTrials.gov Identifier: | NCT00404469 |
| Health Authority: | Denmark: Ethics Committee |
|
Tendinopathy Tendon Injuries Muscular Diseases Musculoskeletal Diseases |
Methylprednisolone Wounds and Injuries Methylprednisolone acetate Disorders of Environmental Origin |
