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Sponsored by: |
UMC Utrecht |
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Information provided by: | UMC Utrecht |
ClinicalTrials.gov Identifier: | NCT00449566 |
The purpose of this study is to investigate brain development in autism by longitudinally assessing children with autism, as well as typically developing controls, using advanced MR techniques. We will use longitudinal diffusion tensor imaging (DTI) measures to investigate the protracted development of long-range white matter fibers in autism. In addition, we will investigate the effect of autism risk genes on brain development.
Condition |
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Autism |
Study Type: | Observational |
Study Design: | Natural History, Longitudinal, Case Control, Prospective Study |
Official Title: | Magnetic Resonance Imaging of Brain Development in Autism |
Ages Eligible for Study: | 6 Years to 18 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Inclusion criteria for subjects with autism
1) DSM-IV (APA, 1994) diagnosis of autism, according to ADI-R interview
Inclusion criteria for controls
Exclusion Criteria:
Contact: Sarah Durston | +31 30 250 8161 | S.Durston@umcutrecht.nl |
Netherlands | |
Dept. of Child and Adolescent Psychiatry, UMC Utrecht | Recruiting |
Utrecht, Netherlands, 3584CX | |
Contact: Marieke Langen, M.Sc. +31 30 250 7084 M.Langen@umcutrecht.nl | |
Principal Investigator: Marieke Langen, M.Sc. | |
Principal Investigator: Hilde Nederveen, M.Sc. |
Principal Investigator: | Sarah Durston, Ph.D. | Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht |
Study Chair: | Herman van Engeland, M.D. Ph.D. | Rudolf Magnust Institute of Neuroscience, UMC Utrecht |
Study ID Numbers: | METC 05/208-K |
Study First Received: | March 18, 2007 |
Last Updated: | March 18, 2007 |
ClinicalTrials.gov Identifier: | NCT00449566 |
Health Authority: | Netherlands: The Central Committee on Research Involving Human Subjects (CCMO) |
Magnetic Resonance Imaging Diffusion Tensor Imaging |
Developmental Disabilities Child Development Disorders, Pervasive Mental Disorders Autistic Disorder Mental Disorders Diagnosed in Childhood |